Zero roll-off retinal MHz-OCT using an FDML-laser

Julian Klee; Jan Philip Kolb; Christin Grill; Wolfgang Draxinger; Tom Pfeiffer; Robert Huber

doi:10.1117/12.2527034

Zero roll-off retinal MHz-OCT using an FDML-laser

Julian Klee, Jan Philip Kolb, Christin Grill, Wolfgang Draxinger, Tom Pfeiffer, Robert Huber

Institute of Biomedical Optics

Abstract

Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.

Original language	English
Title of host publication	Optical Coherence Imaging Techniques and Imaging in Scattering Media III
Editors	Maciej Wojtkowski, Stephen A. Boppart, Wang-Yuhl Oh
Number of pages	3
Volume	11078
Publisher	SPIE
Publication date	19.07.2019
Article number	110780S
ISBN (Print)	978-151062849-6
DOIs	https://doi.org/10.1117/12.2527034
Publication status	Published - 19.07.2019
Event	Optical Coherence Imaging Techniques and Imaging in Scattering Media III 2019 - Munich, Germany Duration: 25.06.2019 → 27.06.2019 Conference number: 152624

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Academic Focus: Biomedical Engineering

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10.1117/12.2527034

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Klee, J., Kolb, J. P., Grill, C., Draxinger, W., Pfeiffer, T., & Huber, R. (2019). Zero roll-off retinal MHz-OCT using an FDML-laser. In M. Wojtkowski, S. A. Boppart, & W-Y. Oh (Eds.), Optical Coherence Imaging Techniques and Imaging in Scattering Media III (Vol. 11078). Article 110780S (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11078). SPIE. https://doi.org/10.1117/12.2527034

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title = "Zero roll-off retinal MHz-OCT using an FDML-laser",

abstract = "Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.",

author = "Julian Klee and Kolb, {Jan Philip} and Christin Grill and Wolfgang Draxinger and Tom Pfeiffer and Robert Huber",

note = "Funding Information: This research was supported by Russian Science Foundation (project No 17-15-01507). Publisher Copyright: {\textcopyright} 2019 SPIE. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.; Optical Coherence Imaging Techniques and Imaging in Scattering Media III 2019 ; Conference date: 25-06-2019 Through 27-06-2019",

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doi = "10.1117/12.2527034",

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Klee, J, Kolb, JP , Grill, C , Draxinger, W, Pfeiffer, T & Huber, R 2019, Zero roll-off retinal MHz-OCT using an FDML-laser. in M Wojtkowski, S A. Boppart & W-Y Oh (eds), Optical Coherence Imaging Techniques and Imaging in Scattering Media III. vol. 11078, 110780S, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11078, SPIE, Optical Coherence Imaging Techniques and Imaging in Scattering Media III 2019 , Munich, Bavaria, Germany, 25.06.19. https://doi.org/10.1117/12.2527034

Zero roll-off retinal MHz-OCT using an FDML-laser. / Klee, Julian; Kolb, Jan Philip ; Grill, Christin et al.
Optical Coherence Imaging Techniques and Imaging in Scattering Media III. ed. / Maciej Wojtkowski; Stephen A. Boppart; Wang-Yuhl Oh. Vol. 11078 SPIE, 2019. 110780S (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11078).

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

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T1 - Zero roll-off retinal MHz-OCT using an FDML-laser

AU - Klee, Julian

AU - Kolb, Jan Philip

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AU - Draxinger, Wolfgang

AU - Pfeiffer, Tom

AU - Huber, Robert

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N2 - Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.

AB - Optical coherence tomography (OCT) applications like ultra-widefield and full eye-length imaging are of high interest for various diagnostic purposes. In swept-source OCT these techniques require a swept light source, which is coherent over the whole imaging depth. We present a zero roll-off 1060 nm Fourier Domain Mode Locked-Laser (FDML-Laser) for retinal OCT imaging at 1.7 MHz A-scan rate and first long-range imaging results with it. Several steps such as improved dispersion compensation and frequency regulation were performed and will be discussed. Besides virtually no loss in OCT signal over the maximum depth range of 4.6 mm and very good dynamic range was observed. Roll-off measurements show no decrease of the point-spread function (PSF), while maintaining a high dynamic range.

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DO - 10.1117/12.2527034

M3 - Conference contribution

SN - 978-151062849-6

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T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Optical Coherence Imaging Techniques and Imaging in Scattering Media III

A2 - Wojtkowski, Maciej

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PB - SPIE

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Y2 - 25 June 2019 through 27 June 2019

ER -

Zero roll-off retinal MHz-OCT using an FDML-laser

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