Wnt signalling in pituitary development and tumorigenesis

T. J.G. Chambers, A. Giles, G. Brabant, J. R.E. Davis*

*Corresponding author for this work
19 Citations (Scopus)


Wnt signalling is activated in both pituitary organogenesis and its mature function. Wnt ligands and Wnt signalling pathways are critical for the regulation of the formation of the pituitary. In the mature pituitary, Wnt signalling pathways control cell activity and may stimulate cell proliferation in both physiological and pathological processes. This review compares Wnt signalling pathways active in the developing and mature pituitary and explores how this gives us further insight into the development of pituitary adenomas.

Original languageEnglish
JournalEndocrine-Related Cancer
Issue number3
Publication statusPublished - 01.06.2013


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