Weniger hormonersatztherapie, weniger brustkrebs in Deutschland?

Translated title of the contribution: Less hormone replacement therapy, less breast cancer in Germany?

Alexander Katalinic*, C. Stegmaier, R. Rawal, A. Waldmann

*Corresponding author for this work
7 Citations (Scopus)


Purpose: The use of hormone replacement therapy (HRT), a known risk factor for the development of breast cancer, has decreased substantially over the last years in the general population, both within Germany and globally. A recent publication from the USA reported a 6.7% decrease in the incidence of breast cancer. The aim of this study was an analysis of current trends in Germany. Material and Methods: The incidence of breast cancer in Germany up until the year 2005 was analyzed using the population-based cancer registers of two federal states: the Saarland (SA) and Schleswig-Holstein (SH). Data on the use of HRT was extracted from a cohort of more than 100000 women who participated in a project on breast cancer diagnostics with quality assurance in the years 2001-2006 in SH. Results: Between 2003 and 2005, the incidence of breast cancer declined in both federal states by 9.5 and 14.3 %, respectively. The strongest decline was seen in the age group between 50 and 69 years, where the decline in both federal states was 19%. The use of HRT began to decline two years before the beginning of the decline in the incidence in breast cancer. In the state of Schleswig-Holstein HRT use declined from 44.9% in 2001 to 14.6% in 2006. Conclusion: On the basis of the present evidence on HRT use and breast cancer incidence, a rapid decline in the incidence of breast cancer is very likely. If this trend is confirmed for the whole of Germany, a decline of (only) 10% would mean approximately 5500 fewer cases of breast cancer per year.

Translated title of the contributionLess hormone replacement therapy, less breast cancer in Germany?
Original languageGerman
JournalGeburtshilfe und Frauenheilkunde
Issue number11
Pages (from-to)1217-1221
Number of pages5
Publication statusPublished - 01.11.2007


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