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Visual processing in migraineurs depends on the migraine cycle

Kerstin Luedtke, Laura H. Schulte, Arne May*

*Corresponding author for this work

Abstract

We investigated changes of after-image duration in migraineurs and healthy controls (HCs) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. Forty-seven episodic (EMs) and 39 chronic migraineurs (CMs; interictal) were compared to 34 HCs for visual after-image duration. Additionally, seven EMs were investigated every consecutive day over 20 to 32 days using the identical paradigm throughout the migraine cycle. Interictally, the after-image duration was shorter compared to HCs, but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs, which oscillates over the migraine cycle. ANN NEUROL 2019;85:280–283.

Original languageEnglish
JournalAnnals of Neurology
Volume85
Issue number2
Pages (from-to)280-283
Number of pages4
ISSN0364-5134
DOIs
Publication statusPublished - 01.02.2019

Funding

This work was supported by the German Research Foundation, SFB936/A5 to A.M. The funding sources did not influence study conduction in any way. We thank Ines Garcia-May for helping with data acquisition, Peter Kropp for providing the image and Jan Mehnert for methodological discussions.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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