Abstract
We investigated changes of after-image duration in migraineurs and healthy controls (HCs) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. Forty-seven episodic (EMs) and 39 chronic migraineurs (CMs; interictal) were compared to 34 HCs for visual after-image duration. Additionally, seven EMs were investigated every consecutive day over 20 to 32 days using the identical paradigm throughout the migraine cycle. Interictally, the after-image duration was shorter compared to HCs, but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs, which oscillates over the migraine cycle. ANN NEUROL 2019;85:280–283.
| Original language | English |
|---|---|
| Journal | Annals of Neurology |
| Volume | 85 |
| Issue number | 2 |
| Pages (from-to) | 280-283 |
| Number of pages | 4 |
| ISSN | 0364-5134 |
| DOIs | |
| Publication status | Published - 01.02.2019 |
Funding
This work was supported by the German Research Foundation, SFB936/A5 to A.M. The funding sources did not influence study conduction in any way. We thank Ines Garcia-May for helping with data acquisition, Peter Kropp for providing the image and Jan Mehnert for methodological discussions.
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
