Visual processing in migraineurs depends on the migraine cycle

Kerstin Luedtke, Laura H. Schulte, Arne May*

*Corresponding author for this work


We investigated changes of after-image duration in migraineurs and healthy controls (HCs) and throughout the migraine cycle to depict changes in the excitatory/inhibitory equilibrium within the visual cortex. Forty-seven episodic (EMs) and 39 chronic migraineurs (CMs; interictal) were compared to 34 HCs for visual after-image duration. Additionally, seven EMs were investigated every consecutive day over 20 to 32 days using the identical paradigm throughout the migraine cycle. Interictally, the after-image duration was shorter compared to HCs, but significantly longer in the ictal compared to interictal phase. These data suggest an altered excitatory/inhibitory equilibrium in migraineurs, which oscillates over the migraine cycle. ANN NEUROL 2019;85:280–283.

Original languageEnglish
JournalAnnals of Neurology
Issue number2
Pages (from-to)280-283
Number of pages4
Publication statusPublished - 01.02.2019

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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