Viral enzymes

Jeroen R. Mesters*, Jinzhi Tan, Rolf Hilgenfeld

*Corresponding author for this work
8 Citations (Scopus)


Viral genomes show unequalled diversity, ranging from single-stranded DNA to double-stranded RNA. Moreover, viruses can quickly adapt to the host's immune response and drug treatment. Although they tend to make optimal use of the host cell's reservoir of proteins, viruses need to carry some enzymatic functions with them, as they may not be available or accessible in the infected cell. Recently, progress has been made in our structural understanding of viral enzymes involved in all stages of the viral life cycle, which includes entry, hijack, replication and exit stages.

Original languageEnglish
JournalCurrent Opinion in Structural Biology
Issue number6
Pages (from-to)776-786
Number of pages11
Publication statusPublished - 01.12.2006

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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