Viral entry and NS1 as potential antiviral drug targets

Aravinda M. de Silva, Félix A. Rey, Paul R. Young, Rolf Hilgenfeld*, Subhash G. Vasudevan

*Corresponding author for this work

Abstract

A general discussion on viral entry and NS1 as potential drug targets was held at the Tofo Advanced Study Week (TASW) on Emerging Viral Diseases in September 2016. The opportunities and gaps for developing therapeutic countermeasures, to take advantage of the high-resolution cryo-electron microscopy structures of dengue and Zika viruses as well as the novel features of NS1 revealed by the 3D structures, were deliberated.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
Number of pages7
Volume1062
Place of PublicationSingapore
PublisherSpringer Singapore
Publication date01.01.2018
Pages107-113
ISBN (Print)978-981-10-8726-4
ISBN (Electronic)978-981-10-8727-1
DOIs
Publication statusPublished - 01.01.2018

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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