Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer

Andreas D. Hartkopf; Tanja N. Fehm; Manfred Welslau; Volkmar Müller; Florian Schütz; Peter A. Fasching; Wolfgang Janni; Isabell Witzel; Christoph Thomssen; Milena Beierlein; Erik Belleville; Michael Untch; Marc Thill; Hans Tesch; Nina Ditsch; Michael P. Lux; Bahriye Aktas; Maggie Banys-Paluchowski; Cornelia Kolberg-Liedtke; Achim Wöckel; Hans Christian Kolberg; Nadia Harbeck; Elmar Stickeler; Rupert Bartsch; Andreas Schneeweiss; Johannes Ettl; Rachel Würstlein; David Krug; Florin Andrei Taran; Diana Lüftner

doi:10.1055/a-2074-0551

Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer

Andreas D. Hartkopf, Tanja N. Fehm, Manfred Welslau, Volkmar Müller, Florian Schütz, Peter A. Fasching^*, Wolfgang Janni, Isabell Witzel, Christoph Thomssen, Milena Beierlein, Erik Belleville, Michael Untch, Marc Thill, Hans Tesch, Nina Ditsch, Michael P. Lux, Bahriye Aktas, Maggie Banys-Paluchowski, Cornelia Kolberg-Liedtke, Achim WöckelHans Christian Kolberg, Nadia Harbeck, Elmar Stickeler, Rupert Bartsch, Andreas Schneeweiss, Johannes Ettl, Rachel Würstlein, David Krug, Florin Andrei Taran, Diana Lüftner

^*Corresponding author for this work

4 Citations (Scopus)

Abstract

With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months.

Original language	English
Journal	Geburtshilfe und Frauenheilkunde
Volume	83
Issue number	6
Pages (from-to)	653-663
Number of pages	11
ISSN	0016-5751
DOIs	https://doi.org/10.1055/a-2074-0551
Publication status	Published - 12.04.2023

Funding

This paper was partly developed as a result of funding from the companies onkowissen.de, Gilead, Lilly, Novartis, Pfizer, and MSD. None of these companies had any part in the preparation of or recommendations made in this manuscript. The authors are solely responsible for the content of the manuscript.

Research Areas and Centers

Research Area: Luebeck Integrated Oncology Network (LION)
Centers: University Cancer Center Schleswig-Holstein (UCCSH)

DFG Research Classification Scheme

2.22-21 Gynaecology and Obstetrics
2.22-14 Hematology, Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/a-2074-0551

Cite this

Hartkopf, A. D., Fehm, T. N., Welslau, M., Müller, V., Schütz, F., Fasching, P. A., Janni, W., Witzel, I., Thomssen, C., Beierlein, M., Belleville, E., Untch, M., Thill, M., Tesch, H., Ditsch, N., Lux, M. P., Aktas, B., Banys-Paluchowski, M., Kolberg-Liedtke, C., ... Lüftner, D. (2023). Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer. Geburtshilfe und Frauenheilkunde, 83(6), 653-663. https://doi.org/10.1055/a-2074-0551

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title = "Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer",

abstract = "With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months.",

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Hartkopf, AD, Fehm, TN, Welslau, M, Müller, V, Schütz, F, Fasching, PA, Janni, W, Witzel, I, Thomssen, C, Beierlein, M, Belleville, E, Untch, M, Thill, M, Tesch, H, Ditsch, N, Lux, MP, Aktas, B, Banys-Paluchowski, M, Kolberg-Liedtke, C, Wöckel, A, Kolberg, HC, Harbeck, N, Stickeler, E, Bartsch, R, Schneeweiss, A, Ettl, J, Würstlein, R, Krug, D, Taran, FA & Lüftner, D 2023, 'Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer', Geburtshilfe und Frauenheilkunde, vol. 83, no. 6, pp. 653-663. https://doi.org/10.1055/a-2074-0551

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T1 - Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer

AU - Hartkopf, Andreas D.

AU - Fehm, Tanja N.

AU - Welslau, Manfred

AU - Müller, Volkmar

AU - Schütz, Florian

AU - Fasching, Peter A.

AU - Janni, Wolfgang

AU - Witzel, Isabell

AU - Thomssen, Christoph

AU - Beierlein, Milena

AU - Belleville, Erik

AU - Untch, Michael

AU - Thill, Marc

AU - Tesch, Hans

AU - Ditsch, Nina

AU - Lux, Michael P.

AU - Aktas, Bahriye

AU - Banys-Paluchowski, Maggie

AU - Kolberg-Liedtke, Cornelia

AU - Wöckel, Achim

AU - Kolberg, Hans Christian

AU - Harbeck, Nadia

AU - Stickeler, Elmar

AU - Bartsch, Rupert

AU - Schneeweiss, Andreas

AU - Ettl, Johannes

AU - Würstlein, Rachel

AU - Krug, David

AU - Taran, Florin Andrei

AU - Lüftner, Diana

PY - 2023/4/12

Y1 - 2023/4/12

N2 - With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months.

AB - With abemaciclib (monarchE study) and olaparib (OlympiA study) gaining approval in the adjuvant treatment setting, a significant change in the standard of care for patients with early stage breast cancer has been established for some time now. Accordingly, some diverse developments are slowly being transferred from the metastatic to the adjuvant treatment setting. Recently, there have also been positive reports of the NATALEE study. Other clinical studies are currently investigating substances that are already established in the metastatic setting. These include, for example, the DESTINY Breast05 study with trastuzumab deruxtecan and the SASCIA study with sacituzumab govitecan. In this review paper, we summarize and place in context the latest developments over the past months.

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DO - 10.1055/a-2074-0551

M3 - Journal articles

AN - SCOPUS:85161638467

SN - 0016-5751

VL - 83

SP - 653

EP - 663

JO - Geburtshilfe und Frauenheilkunde

JF - Geburtshilfe und Frauenheilkunde

IS - 6

ER -

Update Breast Cancer 2023 Part 1 - Early Stage Breast Cancer

Abstract

Funding

Research Areas and Centers

DFG Research Classification Scheme

UN SDGs

Access to Document

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