Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer

Tanja N Fehm; Manfred Welslau; Volkmar Müller; Diana Lüftner; Florian Schütz; Peter A Fasching; Wolfgang Janni; Christoph Thomssen; Isabell Witzel; Milena Beierlein; Erik Belleville; Michael Untch; Marc Thill; Hans Tesch; Nina Ditsch; Michael P Lux; Bahriye Aktas; Maggie Banys-Paluchowski; Cornelia Kolberg-Liedtke; Andreas D Hartkopf; Achim Wöckel; Hans-Christian Kolberg; Nadia Harbeck; Elmar Stickeler

doi:10.1055/a-2018-9053

Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer

Tanja N Fehm, Manfred Welslau, Volkmar Müller, Diana Lüftner, Florian Schütz, Peter A Fasching, Wolfgang Janni, Christoph Thomssen, Isabell Witzel, Milena Beierlein, Erik Belleville, Michael Untch, Marc Thill, Hans Tesch, Nina Ditsch, Michael P Lux, Bahriye Aktas, Maggie Banys-Paluchowski, Cornelia Kolberg-Liedtke, Andreas D HartkopfAchim Wöckel, Hans-Christian Kolberg, Nadia Harbeck, Elmar Stickeler

Clinic of Gynecology and Obstetrics

Abstract

The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies.

Original language	English
Journal	Geburtshilfe und Frauenheilkunde
Volume	83
Issue number	03
Pages (from-to)	289-298
Number of pages	10
ISSN	0016-5751
DOIs	https://doi.org/10.1055/a-2018-9053
Publication status	Published - 03.2023

Research Areas and Centers

Centers: University Cancer Center Schleswig-Holstein (UCCSH)
Research Area: Luebeck Integrated Oncology Network (LION)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/a-2018-9053

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Fehm, T. N., Welslau, M., Müller, V., Lüftner, D., Schütz, F., Fasching, P. A., Janni, W., Thomssen, C., Witzel, I., Beierlein, M., Belleville, E., Untch, M., Thill, M., Tesch, H., Ditsch, N., Lux, M. P., Aktas, B., Banys-Paluchowski, M., Kolberg-Liedtke, C., ... Stickeler, E. (2023). Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer. Geburtshilfe und Frauenheilkunde, 83(03), 289-298. https://doi.org/10.1055/a-2018-9053

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title = "Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer",

abstract = "The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies.",

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Fehm, TN, Welslau, M, Müller, V, Lüftner, D, Schütz, F, Fasching, PA, Janni, W, Thomssen, C, Witzel, I, Beierlein, M, Belleville, E, Untch, M, Thill, M, Tesch, H, Ditsch, N, Lux, MP, Aktas, B, Banys-Paluchowski, M, Kolberg-Liedtke, C, Hartkopf, AD, Wöckel, A, Kolberg, H-C, Harbeck, N & Stickeler, E 2023, 'Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer', Geburtshilfe und Frauenheilkunde, vol. 83, no. 03, pp. 289-298. https://doi.org/10.1055/a-2018-9053

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AU - Fehm, Tanja N

AU - Welslau, Manfred

AU - Müller, Volkmar

AU - Lüftner, Diana

AU - Schütz, Florian

AU - Fasching, Peter A

AU - Janni, Wolfgang

AU - Thomssen, Christoph

AU - Witzel, Isabell

AU - Beierlein, Milena

AU - Belleville, Erik

AU - Untch, Michael

AU - Thill, Marc

AU - Tesch, Hans

AU - Ditsch, Nina

AU - Lux, Michael P

AU - Aktas, Bahriye

AU - Banys-Paluchowski, Maggie

AU - Kolberg-Liedtke, Cornelia

AU - Hartkopf, Andreas D

AU - Wöckel, Achim

AU - Kolberg, Hans-Christian

AU - Harbeck, Nadia

AU - Stickeler, Elmar

N1 - The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).

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N2 - The treatment of patients with early stage breast cancer has changed in recent years due to the introduction of pembrolizumab, olaparib, and abemaciclib. These and other drugs with the same class of active ingredient are currently in trial for various indications. This review article summarizes the latest results that have either been presented at major conferences such as the ESMO 2022 or published recently in international journals. This includes reports on newly discovered breast cancer genes, atezolizumab in neoadjuvant therapy in HER2-positive patients, long-term data from the APHINITY study, and on how preoperative peritumoral application of local anesthetics can influence the prognosis. We also present solid data on dynamic Ki-67 from the ADAPT studies.

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Update Breast Cancer 2022 Part 5 - Early Stage Breast Cancer

Abstract

Research Areas and Centers

UN SDGs

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