Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis

Gonzalo Salazar de Pablo; Andrea De Micheli; Dorien H Nieman; Christoph U Correll; Lars Vedel Kessing; Andrea Pfennig; Andreas Bechdolf; Stefan Borgwardt; Celso Arango; Therese van Amelsvoort; Eduard Vieta; Marco Solmi; Dominic Oliver; Ana Catalan; Valeria Verdino; Lucia Di Maggio; Ilaria Bonoldi; Julio Vaquerizo-Serrano; Ottone Baccaredda Boy; Umberto Provenzani; Francesca Ruzzi; Federica Calorio; Guido Nosari; Benedetto Di Marco; Irene Famularo; Silvia Molteni; Eleonora Filosi; Martina Mensi; Umberto Balottin; Pierluigi Politi; Jae Il Shin; Paolo Fusar-Poli

doi:10.1016/j.euroneuro.2020.10.007

Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis

Gonzalo Salazar de Pablo, Andrea De Micheli, Dorien H Nieman, Christoph U Correll, Lars Vedel Kessing, Andrea Pfennig, Andreas Bechdolf, Stefan Borgwardt, Celso Arango, Therese van Amelsvoort, Eduard Vieta, Marco Solmi, Dominic Oliver, Ana Catalan, Valeria Verdino, Lucia Di Maggio, Ilaria Bonoldi, Julio Vaquerizo-Serrano, Ottone Baccaredda Boy, Umberto ProvenzaniFrancesca Ruzzi, Federica Calorio, Guido Nosari, Benedetto Di Marco, Irene Famularo, Silvia Molteni, Eleonora Filosi, Martina Mensi, Umberto Balottin, Pierluigi Politi, Jae Il Shin, Paolo Fusar-Poli

Department of Psychiatry, Psychosomatics and Psychotherapie

92 Citations (Scopus)

Abstract

Promotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic PRISMA/RIGHT-compliant meta-analysis (PROSPERO: CRD42018088708) search of Web of Science until 04/31/2019 identified original studies comparing the efficacy of universal/selective interventions for good mental health vs a control group, in samples with a mean age <35 years. Meta-analytical random-effects model, heterogeneity statistics, assessment of publication bias, study quality and sensitivity analyses investigated the efficacy (Hedges' g=effect size, ES) of universal/selective interventions to promote 14 good mental health outcomes defined a-priori. 276 studies were included (total participants: 159,508, 79,142 interventions and 80,366 controls), mean age=15.0 (SD=7.4); female=56.0%. There was a significant overall improvement in 10/13 good mental health outcome categories that could be meta-analysed: compared to controls, interventions significantly improved (in descending order of magnitude) mental health literacy (ES=0.685, p<0.001), emotions (ES=0.541, p<0.001), self-perceptions and values (ES=0.49, p<0.001), quality of life (ES=0.457, p=0.001), cognitive skills (ES=0.428, p<0.001), social skills (ES=0.371, p<0.001), physical health (ES=0.285, p<0.001), sexual health (ES=0.257, p=0.017), academic/occupational performance (ES=0.211, p<0.001) and attitude towards mental disorders (ES=0.177, p=0.006). Psychoeducation was the most effective intervention for promoting mental health literacy (ES=0.774, p<0.001) and cognitive skills (ES=1.153, p=0.03). Physical therapy, exercise and relaxation were more effective than psychoeducation and psychotherapy for promoting physical health (ES=0.498, p<0.001). In conclusion, several universal/selective interventions can be effective to promote good mental health in young people. Future research should consolidate and extend these findings.

Original language	English
Journal	European Neuropsychopharmacology
Volume	41
Pages (from-to)	28-39
Number of pages	12
ISSN	0924-977X
DOIs	https://doi.org/10.1016/j.euroneuro.2020.10.007
Publication status	Published - 12.2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

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10.1016/j.euroneuro.2020.10.007

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Salazar de Pablo, G., De Micheli, A., Nieman, D. H., Correll, C. U., Kessing, L. V., Pfennig, A., Bechdolf, A., Borgwardt, S., Arango, C., van Amelsvoort, T., Vieta, E., Solmi, M., Oliver, D., Catalan, A., Verdino, V., Di Maggio, L., Bonoldi, I., Vaquerizo-Serrano, J., Baccaredda Boy, O., ... Fusar-Poli, P. (2020). Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis. European Neuropsychopharmacology, 41, 28-39. https://doi.org/10.1016/j.euroneuro.2020.10.007

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title = "Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis",

abstract = "Promotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic PRISMA/RIGHT-compliant meta-analysis (PROSPERO: CRD42018088708) search of Web of Science until 04/31/2019 identified original studies comparing the efficacy of universal/selective interventions for good mental health vs a control group, in samples with a mean age <35 years. Meta-analytical random-effects model, heterogeneity statistics, assessment of publication bias, study quality and sensitivity analyses investigated the efficacy (Hedges' g=effect size, ES) of universal/selective interventions to promote 14 good mental health outcomes defined a-priori. 276 studies were included (total participants: 159,508, 79,142 interventions and 80,366 controls), mean age=15.0 (SD=7.4); female=56.0\%. There was a significant overall improvement in 10/13 good mental health outcome categories that could be meta-analysed: compared to controls, interventions significantly improved (in descending order of magnitude) mental health literacy (ES=0.685, p<0.001), emotions (ES=0.541, p<0.001), self-perceptions and values (ES=0.49, p<0.001), quality of life (ES=0.457, p=0.001), cognitive skills (ES=0.428, p<0.001), social skills (ES=0.371, p<0.001), physical health (ES=0.285, p<0.001), sexual health (ES=0.257, p=0.017), academic/occupational performance (ES=0.211, p<0.001) and attitude towards mental disorders (ES=0.177, p=0.006). Psychoeducation was the most effective intervention for promoting mental health literacy (ES=0.774, p<0.001) and cognitive skills (ES=1.153, p=0.03). Physical therapy, exercise and relaxation were more effective than psychoeducation and psychotherapy for promoting physical health (ES=0.498, p<0.001). In conclusion, several universal/selective interventions can be effective to promote good mental health in young people. Future research should consolidate and extend these findings.",

author = "\{Salazar de Pablo\}, Gonzalo and \{De Micheli\}, Andrea and Nieman, \{Dorien H\} and Correll, \{Christoph U\} and Kessing, \{Lars Vedel\} and Andrea Pfennig and Andreas Bechdolf and Stefan Borgwardt and Celso Arango and \{van Amelsvoort\}, Therese and Eduard Vieta and Marco Solmi and Dominic Oliver and Ana Catalan and Valeria Verdino and \{Di Maggio\}, Lucia and Ilaria Bonoldi and Julio Vaquerizo-Serrano and \{Baccaredda Boy\}, Ottone and Umberto Provenzani and Francesca Ruzzi and Federica Calorio and Guido Nosari and \{Di Marco\}, Benedetto and Irene Famularo and Silvia Molteni and Eleonora Filosi and Martina Mensi and Umberto Balottin and Pierluigi Politi and Shin, \{Jae Il\} and Paolo Fusar-Poli",

note = "Copyright {\textcopyright} 2020. Published by Elsevier B.V.",

year = "2020",

month = dec,

doi = "10.1016/j.euroneuro.2020.10.007",

language = "English",

volume = "41",

pages = "28--39",

journal = "European Neuropsychopharmacology",

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publisher = "Elsevier B.V.",

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Salazar de Pablo, G, De Micheli, A, Nieman, DH, Correll, CU, Kessing, LV, Pfennig, A, Bechdolf, A, Borgwardt, S, Arango, C, van Amelsvoort, T, Vieta, E, Solmi, M, Oliver, D, Catalan, A, Verdino, V, Di Maggio, L, Bonoldi, I, Vaquerizo-Serrano, J, Baccaredda Boy, O, Provenzani, U, Ruzzi, F, Calorio, F, Nosari, G, Di Marco, B, Famularo, I, Molteni, S, Filosi, E, Mensi, M, Balottin, U, Politi, P, Shin, JI & Fusar-Poli, P 2020, 'Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis', European Neuropsychopharmacology, vol. 41, pp. 28-39. https://doi.org/10.1016/j.euroneuro.2020.10.007

TY - JOUR

T1 - Universal and selective interventions to promote good mental health in young people

T2 - Systematic review and meta-analysis

AU - Salazar de Pablo, Gonzalo

AU - De Micheli, Andrea

AU - Nieman, Dorien H

AU - Correll, Christoph U

AU - Kessing, Lars Vedel

AU - Pfennig, Andrea

AU - Bechdolf, Andreas

AU - Borgwardt, Stefan

AU - Arango, Celso

AU - van Amelsvoort, Therese

AU - Vieta, Eduard

AU - Solmi, Marco

AU - Oliver, Dominic

AU - Catalan, Ana

AU - Verdino, Valeria

AU - Di Maggio, Lucia

AU - Bonoldi, Ilaria

AU - Vaquerizo-Serrano, Julio

AU - Baccaredda Boy, Ottone

AU - Provenzani, Umberto

AU - Ruzzi, Francesca

AU - Calorio, Federica

AU - Nosari, Guido

AU - Di Marco, Benedetto

AU - Famularo, Irene

AU - Molteni, Silvia

AU - Filosi, Eleonora

AU - Mensi, Martina

AU - Balottin, Umberto

AU - Politi, Pierluigi

AU - Shin, Jae Il

AU - Fusar-Poli, Paolo

PY - 2020/12

Y1 - 2020/12

N2 - Promotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic PRISMA/RIGHT-compliant meta-analysis (PROSPERO: CRD42018088708) search of Web of Science until 04/31/2019 identified original studies comparing the efficacy of universal/selective interventions for good mental health vs a control group, in samples with a mean age <35 years. Meta-analytical random-effects model, heterogeneity statistics, assessment of publication bias, study quality and sensitivity analyses investigated the efficacy (Hedges' g=effect size, ES) of universal/selective interventions to promote 14 good mental health outcomes defined a-priori. 276 studies were included (total participants: 159,508, 79,142 interventions and 80,366 controls), mean age=15.0 (SD=7.4); female=56.0%. There was a significant overall improvement in 10/13 good mental health outcome categories that could be meta-analysed: compared to controls, interventions significantly improved (in descending order of magnitude) mental health literacy (ES=0.685, p<0.001), emotions (ES=0.541, p<0.001), self-perceptions and values (ES=0.49, p<0.001), quality of life (ES=0.457, p=0.001), cognitive skills (ES=0.428, p<0.001), social skills (ES=0.371, p<0.001), physical health (ES=0.285, p<0.001), sexual health (ES=0.257, p=0.017), academic/occupational performance (ES=0.211, p<0.001) and attitude towards mental disorders (ES=0.177, p=0.006). Psychoeducation was the most effective intervention for promoting mental health literacy (ES=0.774, p<0.001) and cognitive skills (ES=1.153, p=0.03). Physical therapy, exercise and relaxation were more effective than psychoeducation and psychotherapy for promoting physical health (ES=0.498, p<0.001). In conclusion, several universal/selective interventions can be effective to promote good mental health in young people. Future research should consolidate and extend these findings.

AB - Promotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic PRISMA/RIGHT-compliant meta-analysis (PROSPERO: CRD42018088708) search of Web of Science until 04/31/2019 identified original studies comparing the efficacy of universal/selective interventions for good mental health vs a control group, in samples with a mean age <35 years. Meta-analytical random-effects model, heterogeneity statistics, assessment of publication bias, study quality and sensitivity analyses investigated the efficacy (Hedges' g=effect size, ES) of universal/selective interventions to promote 14 good mental health outcomes defined a-priori. 276 studies were included (total participants: 159,508, 79,142 interventions and 80,366 controls), mean age=15.0 (SD=7.4); female=56.0%. There was a significant overall improvement in 10/13 good mental health outcome categories that could be meta-analysed: compared to controls, interventions significantly improved (in descending order of magnitude) mental health literacy (ES=0.685, p<0.001), emotions (ES=0.541, p<0.001), self-perceptions and values (ES=0.49, p<0.001), quality of life (ES=0.457, p=0.001), cognitive skills (ES=0.428, p<0.001), social skills (ES=0.371, p<0.001), physical health (ES=0.285, p<0.001), sexual health (ES=0.257, p=0.017), academic/occupational performance (ES=0.211, p<0.001) and attitude towards mental disorders (ES=0.177, p=0.006). Psychoeducation was the most effective intervention for promoting mental health literacy (ES=0.774, p<0.001) and cognitive skills (ES=1.153, p=0.03). Physical therapy, exercise and relaxation were more effective than psychoeducation and psychotherapy for promoting physical health (ES=0.498, p<0.001). In conclusion, several universal/selective interventions can be effective to promote good mental health in young people. Future research should consolidate and extend these findings.

U2 - 10.1016/j.euroneuro.2020.10.007

DO - 10.1016/j.euroneuro.2020.10.007

M3 - Scientific review articles

C2 - 33162291

SN - 0924-977X

VL - 41

SP - 28

EP - 39

JO - European Neuropsychopharmacology

JF - European Neuropsychopharmacology

ER -

Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis

Abstract

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