Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)

F. Schaumburg; E. A. Idelevich; G. Peters; A. Mellmann; C. von Eiff; K. Becker; M. Abele-Horn; M. Aepfelbacher; F. Albert; A. Anders; W. Bär; B. Beyreiß; G. Bierbaum; U. Bührlen; K. H.U. Borg; K. Claußen; C. Diaz; A. Ditzen; M. Dobonici; U. Eigner; H. Erichsen; A. Fahr; P. Finzer; U. Frank; A. Friedrich; M. Frosch; G. Funke; S. Gatermann; J. Geisen; W. Hell; M. Herrmann; U. Höffler; E. Jacobs; B. Jansen; D. Jonas; M. Kaase; W. Kalka-Moll; M. Kaulfers; J. K. Knobloch; M. Kresken; B. Körber-Irrgang; M. van der Linden; A. Lommel; C. Lücking; D. Mack; S. Monecke; S. Müller; L. von Müller; M. Trautmann

doi:10.1111/1469-0691.12519

Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)

F. Schaumburg^*, E. A. Idelevich, G. Peters, A. Mellmann, C. von Eiff, K. Becker, M. Abele-Horn, M. Aepfelbacher, F. Albert, A. Anders, W. Bär, B. Beyreiß, G. Bierbaum, U. Bührlen, K. H.U. Borg, K. Claußen, C. Diaz, A. Ditzen, M. Dobonici, U. EignerH. Erichsen, A. Fahr, P. Finzer, U. Frank, A. Friedrich, M. Frosch, G. Funke, S. Gatermann, J. Geisen, W. Hell, M. Herrmann, U. Höffler, E. Jacobs, B. Jansen, D. Jonas, M. Kaase, W. Kalka-Moll, M. Kaulfers, J. K. Knobloch, M. Kresken, B. Körber-Irrgang, M. van der Linden, A. Lommel, C. Lücking, D. Mack, S. Monecke, S. Müller, L. von Müller, M. Trautmann

^*Corresponding author for this work

8 Citations (Scopus)

Abstract

We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.

Original language	English
Journal	Clinical Microbiology and Infection
Volume	20
Issue number	9
Pages (from-to)	O554-O557
ISSN	1198-743X
DOIs	https://doi.org/10.1111/1469-0691.12519
Publication status	Published - 01.09.2014

Funding

In addition to the authors, the following persons (in alphabetical order) were participants in the study group: M. Abele-Horn, Würzburg; M. Aepfelbacher, Hamburg; F. Albert, Erlangen; A. Anders, Bochum; W. Bär and B. Beyreiß, Cottbus; G. Bierbaum, Bonn; U. Bührlen, Stuttgart; K. H.-U. Borg, Hamburg; K. Claußen, Hannover; C. Diaz, Köln; A. Ditzen, Dresden; M. Dobonici, Ludwigshafen; U. Eigner, Heidelberg; H. Erichsen, Moers; A. Fahr, Heidelberg; P. Finzer, Moers; U. Frank, Freiburg; A. Friedrich, Münster; C. Freytag, Bad-Oeynhausen; M. Frosch, Würzburg; G. Funke, Ravensburg; S. Gatermann, Bochum; J. Geisen, Köln; W. Hell, Koblenz; M. Herrmann, Homburg; U. Höffler, Ludwigshafen; E. Jacobs, Dresden; B. Jansen, Mainz; D. Jonas, Freiburg; M. Kaase, Bochum; W. Kalka-Moll, Mönchengladbach; M. Kaulfers and J. K. Knobloch, Hamburg; M. Kresken and B. Körber-Irrgang, Rheinbach; M. van der Linden, Aachen; A. Lommel and C. Lücking, Ludwigshafen; D. Mack, Hamburg; S. Monecke, Dresden; S. Müller, Würzburg; L. von Müller, Homburg; A. Müller-Chorus, Bochum; K. Noldt, Hamburg; W. Pfister, Jena; T. Regnath and W. Reiter, Stuttgart; R. R. Reinert, Aachen; J. Rissland, Koblenz; A. Roggenkamp, München; U. Rohr, Bochum; E. Rosenthal, Wiesbaden; S. Schade and S. Scherpe, Hamburg; T. Schmidt-Wieland, Ravensburg; C. Schoerner, Erlangen; S. Schubert, Kiel; R. Schwarz, Köln; R. Schwarz, Mönchengladbach; K. Schwegmann, Hannover; H. Seifert, Köln; V. Simon, München; E. Straube, Jena; M. Trautmann, Stuttgart; U. Ullmann, Kiel; U. Vogel, Würzburg; M. Vogt, Koblenz; H. von Wulffen, Hamburg; T. Wichelhaus, Frankfurt; M. L. Wimmer-Dahmen, Mönchengladbach; J. Wüllenweber, Homburg; B. Würstl, München; and B. Zöllner, Moers. This work was supported in part by the Paul Ehrlich Gesellschaft für Chemotherapie (PEG) (to K. Becker and C. von Eiff) under the auspice of the working group ‘Staphylococcal infections’ of the PEG, and by grants to G. Peters and K. Becker (01KI1014A) within the MedVet-Staph project by the Bundesministerium für Bildung und Forschung (BMBF).

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Schaumburg, F., Idelevich, E. A., Peters, G., Mellmann, A., von Eiff, C., Becker, K., Abele-Horn, M., Aepfelbacher, M., Albert, F., Anders, A., Bär, W., Beyreiß, B., Bierbaum, G., Bührlen, U., Borg, K. H. U., Claußen, K., Diaz, C., Ditzen, A., Dobonici, M., ... Trautmann, M. (2014). Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011). Clinical Microbiology and Infection, 20(9), O554-O557. https://doi.org/10.1111/1469-0691.12519

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title = "Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)",

abstract = "We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.",

author = "F. Schaumburg and Idelevich, \{E. A.\} and G. Peters and A. Mellmann and \{von Eiff\}, C. and K. Becker and M. Abele-Horn and M. Aepfelbacher and F. Albert and A. Anders and W. B{\"a}r and B. Beyrei{\ss} and G. Bierbaum and U. B{\"u}hrlen and Borg, \{K. H.U.\} and K. Clau{\ss}en and C. Diaz and A. Ditzen and M. Dobonici and U. Eigner and H. Erichsen and A. Fahr and P. Finzer and U. Frank and A. Friedrich and M. Frosch and G. Funke and S. Gatermann and J. Geisen and W. Hell and M. Herrmann and U. H{\"o}ffler and E. Jacobs and B. Jansen and D. Jonas and M. Kaase and W. Kalka-Moll and M. Kaulfers and Knobloch, \{J. K.\} and M. Kresken and B. K{\"o}rber-Irrgang and \{van der Linden\}, M. and A. Lommel and C. L{\"u}cking and D. Mack and S. Monecke and S. M{\"u}ller and \{von M{\"u}ller\}, L. and M. Trautmann",

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Schaumburg, F, Idelevich, EA, Peters, G, Mellmann, A, von Eiff, C, Becker, K, Abele-Horn, M, Aepfelbacher, M, Albert, F, Anders, A, Bär, W, Beyreiß, B, Bierbaum, G, Bührlen, U, Borg, KHU, Claußen, K, Diaz, C, Ditzen, A, Dobonici, M, Eigner, U, Erichsen, H, Fahr, A, Finzer, P, Frank, U, Friedrich, A, Frosch, M, Funke, G, Gatermann, S, Geisen, J, Hell, W, Herrmann, M, Höffler, U, Jacobs, E, Jansen, B, Jonas, D, Kaase, M, Kalka-Moll, W, Kaulfers, M, Knobloch, JK, Kresken, M, Körber-Irrgang, B, van der Linden, M, Lommel, A, Lücking, C, Mack, D, Monecke, S, Müller, S, von Müller, L & Trautmann, M 2014, 'Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)', Clinical Microbiology and Infection, vol. 20, no. 9, pp. O554-O557. https://doi.org/10.1111/1469-0691.12519

TY - JOUR

T1 - Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)

AU - Schaumburg, F.

AU - Idelevich, E. A.

AU - Peters, G.

AU - Mellmann, A.

AU - von Eiff, C.

AU - Becker, K.

AU - Abele-Horn, M.

AU - Aepfelbacher, M.

AU - Albert, F.

AU - Anders, A.

AU - Bär, W.

AU - Beyreiß, B.

AU - Bierbaum, G.

AU - Bührlen, U.

AU - Borg, K. H.U.

AU - Claußen, K.

AU - Diaz, C.

AU - Ditzen, A.

AU - Dobonici, M.

AU - Eigner, U.

AU - Erichsen, H.

AU - Fahr, A.

AU - Finzer, P.

AU - Frank, U.

AU - Friedrich, A.

AU - Frosch, M.

AU - Funke, G.

AU - Gatermann, S.

AU - Geisen, J.

AU - Hell, W.

AU - Herrmann, M.

AU - Höffler, U.

AU - Jacobs, E.

AU - Jansen, B.

AU - Jonas, D.

AU - Kaase, M.

AU - Kalka-Moll, W.

AU - Kaulfers, M.

AU - Knobloch, J. K.

AU - Kresken, M.

AU - Körber-Irrgang, B.

AU - van der Linden, M.

AU - Lommel, A.

AU - Lücking, C.

AU - Mack, D.

AU - Monecke, S.

AU - Müller, S.

AU - von Müller, L.

AU - Trautmann, M.

PY - 2014/9/1

Y1 - 2014/9/1

N2 - We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.

AB - We analysed trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus (MSRA) from Germany to assess the impact of the changing population structure of MRSA on antimicrobial resistance rates. During two large nationwide multicentre studies in 2004-2005 and 2010-2011, we collected consecutively spa-genotyped MRSA isolates. The increase in non-susceptibility rates for tetracycline and trimethoprim-sulphamethoxazole was associated with the spread of livestock-associated MRSA. A decrease in non-susceptibility rates for aminoglycosides and quinolones affected all major lineages (spa-clonal complexes 003, 008, and 032). All isolated remained susceptible to glycopeptides and linezolid.

UR - https://www.scopus.com/pages/publications/84908029998

U2 - 10.1111/1469-0691.12519

DO - 10.1111/1469-0691.12519

M3 - Journal articles

C2 - 24372797

AN - SCOPUS:84908029998

SN - 1198-743X

VL - 20

SP - O554-O557

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 9

ER -

Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004-2011)

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