Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

Christian Benedict; Andrew J. Ghio; Hartmut Gehring; Bernd Schultes; Achim Peters; Kerstin M. Oltmanns

doi:10.3324/haematol.10637

Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

Christian Benedict^*, Andrew J. Ghio, Hartmut Gehring, Bernd Schultes, Achim Peters, Kerstin M. Oltmanns

^*Corresponding author for this work

9 Citations (Scopus)

Abstract

To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).

Original language	English
Journal	Haematologica
Volume	92
Issue number	1
Pages (from-to)	125-126
Number of pages	2
ISSN	0390-6078
DOIs	https://doi.org/10.3324/haematol.10637
Publication status	Published - 01.2007

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Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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10.3324/haematol.10637

Cite this

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title = "Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men",

abstract = "To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).",

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T1 - Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

AU - Benedict, Christian

AU - Ghio, Andrew J.

AU - Gehring, Hartmut

AU - Schultes, Bernd

AU - Peters, Achim

AU - Oltmanns, Kerstin M.

PY - 2007/1

Y1 - 2007/1

N2 - To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).

AB - To determine the impact of acute hypoxia on prohepcidin concentrations in humans, we measured concentrations of this peptide in serum collected during and after a transient period (30 min) of hypoxia and during normoxia. Prohepcidin concentrations were significantly lower 150 min after the end of hypoxia than after normoxia (p=0.028).

UR - https://www.scopus.com/pages/publications/33846899729

U2 - 10.3324/haematol.10637

DO - 10.3324/haematol.10637

M3 - Journal articles

C2 - 17229646

AN - SCOPUS:33846899729

SN - 0390-6078

VL - 92

SP - 125

EP - 126

JO - Haematologica

JF - Haematologica

IS - 1

ER -

Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men

Abstract

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