Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT

Madita Göb; Sazgar Burhan; Simon Lotz; Robert Huber

doi:10.1117/12.2612171

Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT

Madita Göb, Sazgar Burhan, Simon Lotz, Robert Huber

Institute of Biomedical Optics

3 Citations (Scopus)

Abstract

We demonstrate ultra-large field of view OCT scanning using standard optics, a X-Y-galvanometer scanner and a synchronously driven motorized XYZ-positioning stage. The integration of a movable stage into our self-built 3.3 MHz- OCT system allows acquiring coherent ultra-large area images, fully leveraging the high speed potential of our system. For fast OCT-angiography, one galvanometer axis scanner is driven in a repetitive sawtooth pattern, fully synchronized to the movement of the linear stage, to obtain multiple measurements at each position. This technique requires exact synchronization, precise repositioning, and uniform movements with low tolerances to ensure a minimum revisitation error. We analyze error and performance of our setup and demonstrate angiographic imaging.

Original language	English
Title of host publication	SOIE BIOS : Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI
Number of pages	31
Volume	11948
Place of Publication	San Francisco, USA
Publication date	07.03.2022
Pages	27
DOIs	https://doi.org/10.1117/12.2612171
Publication status	Published - 07.03.2022

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Academic Focus: Biomedical Engineering

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title = "Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT",

abstract = "We demonstrate ultra-large field of view OCT scanning using standard optics, a X-Y-galvanometer scanner and a synchronously driven motorized XYZ-positioning stage. The integration of a movable stage into our self-built 3.3 MHz- OCT system allows acquiring coherent ultra-large area images, fully leveraging the high speed potential of our system. For fast OCT-angiography, one galvanometer axis scanner is driven in a repetitive sawtooth pattern, fully synchronized to the movement of the linear stage, to obtain multiple measurements at each position. This technique requires exact synchronization, precise repositioning, and uniform movements with low tolerances to ensure a minimum revisitation error. We analyze error and performance of our setup and demonstrate angiographic imaging.",

author = "Madita G{\"o}b and Sazgar Burhan and Simon Lotz and Robert Huber",

note = "@inproceedings\{Goeb2022BiOS, author = \{M. G{\"o}b, S. Burhan, S. Lotz and R. Huber\}, title = \{\{Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT\}\}, volume = \{11948\}, booktitle = \{Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI\}, editor = \{Joseph A. Izatt and James G. Fujimoto\}, organization = \{International Society for Optics and Photonics\}, publisher = \{SPIE\}, pages = \{27 -- 31\}, keywords = \{AG-Huber\_FDML, AG-Huber\_OCT, Optical Coherence Tomography, Fourier Domain Mode Locking, FDML, Optical Coherence Angiography, OCTA, Medical optics and biotechnology, Medical imaging, Three-dimensional image acquisition, Scanners, Microscopy\}, year = \{2022\}, doi = \{10.1117/12.2612171\}, \}",

year = "2022",

month = mar,

day = "7",

doi = "10.1117/12.2612171",

language = "English",

volume = "11948",

pages = "27",

booktitle = "SOIE BIOS",

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Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT. / Göb, Madita; Burhan, Sazgar; Lotz, Simon et al.
SOIE BIOS: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI. Vol. 11948 San Francisco, USA, 2022. p. 27.

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT

AU - Göb, Madita

AU - Burhan, Sazgar

AU - Lotz, Simon

AU - Huber, Robert

N1 - @inproceedings{Goeb2022BiOS, author = {M. Göb, S. Burhan, S. Lotz and R. Huber}, title = {{Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT}}, volume = {11948}, booktitle = {Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI}, editor = {Joseph A. Izatt and James G. Fujimoto}, organization = {International Society for Optics and Photonics}, publisher = {SPIE}, pages = {27 -- 31}, keywords = {AG-Huber_FDML, AG-Huber_OCT, Optical Coherence Tomography, Fourier Domain Mode Locking, FDML, Optical Coherence Angiography, OCTA, Medical optics and biotechnology, Medical imaging, Three-dimensional image acquisition, Scanners, Microscopy}, year = {2022}, doi = {10.1117/12.2612171}, }

PY - 2022/3/7

Y1 - 2022/3/7

N2 - We demonstrate ultra-large field of view OCT scanning using standard optics, a X-Y-galvanometer scanner and a synchronously driven motorized XYZ-positioning stage. The integration of a movable stage into our self-built 3.3 MHz- OCT system allows acquiring coherent ultra-large area images, fully leveraging the high speed potential of our system. For fast OCT-angiography, one galvanometer axis scanner is driven in a repetitive sawtooth pattern, fully synchronized to the movement of the linear stage, to obtain multiple measurements at each position. This technique requires exact synchronization, precise repositioning, and uniform movements with low tolerances to ensure a minimum revisitation error. We analyze error and performance of our setup and demonstrate angiographic imaging.

AB - We demonstrate ultra-large field of view OCT scanning using standard optics, a X-Y-galvanometer scanner and a synchronously driven motorized XYZ-positioning stage. The integration of a movable stage into our self-built 3.3 MHz- OCT system allows acquiring coherent ultra-large area images, fully leveraging the high speed potential of our system. For fast OCT-angiography, one galvanometer axis scanner is driven in a repetitive sawtooth pattern, fully synchronized to the movement of the linear stage, to obtain multiple measurements at each position. This technique requires exact synchronization, precise repositioning, and uniform movements with low tolerances to ensure a minimum revisitation error. We analyze error and performance of our setup and demonstrate angiographic imaging.

UR - https://zenodo.org/records/19851724

U2 - 10.1117/12.2612171

DO - 10.1117/12.2612171

M3 - Conference contribution

VL - 11948

SP - 27

BT - SOIE BIOS

CY - San Francisco, USA

ER -

Towards ultra-large area vascular contrast skin imaging using multi-MHz-OCT

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