TY - JOUR
T1 - Tissue microarrays in clinical urology - Technical considerations
AU - Kramer, Mario W.
AU - Merseburger, Axel S.
AU - Hennenlotter, Jörg
AU - Kuczyk, Markus
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - The tissue microarray (TMA) technique is a 'high-throughput' tool which enables a rapid and concurrent analysis of molecular targets in large numbers of specimens at the DNA, RNA and protein levels under standardized conditions. In addition, TMA is a cost- and time-efficient method. This review focuses on its technical side, outlining its advantages and weaknesses. It also gives an overview of some major studies of bladder and prostate cancer in which the TMA technique was used.
AB - The tissue microarray (TMA) technique is a 'high-throughput' tool which enables a rapid and concurrent analysis of molecular targets in large numbers of specimens at the DNA, RNA and protein levels under standardized conditions. In addition, TMA is a cost- and time-efficient method. This review focuses on its technical side, outlining its advantages and weaknesses. It also gives an overview of some major studies of bladder and prostate cancer in which the TMA technique was used.
UR - http://www.scopus.com/inward/record.url?scp=36749036689&partnerID=8YFLogxK
U2 - 10.1080/00365590701430737
DO - 10.1080/00365590701430737
M3 - Scientific review articles
C2 - 17907050
AN - SCOPUS:36749036689
SN - 0036-5599
VL - 41
SP - 478
EP - 484
JO - Scandinavian Journal of Urology and Nephrology
JF - Scandinavian Journal of Urology and Nephrology
IS - 6
ER -