Tissue microarrays: Applications in urological cancer research

A. S. Merseburger; A. G. Anastasiadis; J. Hennenlotter; D. Schilling; P. Simon; S. A. Machtens; J. Serth; Arnulf Stenzl; Markus A. Kuczyk

doi:10.1007/s00345-006-0103-1

Tissue microarrays: Applications in urological cancer research

A. S. Merseburger, A. G. Anastasiadis, J. Hennenlotter, D. Schilling, P. Simon, S. A. Machtens, J. Serth, Arnulf Stenzl, Markus A. Kuczyk^*

^*Corresponding author for this work

Department of Urology

9 Citations (Scopus)

Abstract

Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.

Original language	English
Journal	World Journal of Urology
Volume	24
Issue number	5
Pages (from-to)	579-584
Number of pages	6
ISSN	0724-4983
DOIs	https://doi.org/10.1007/s00345-006-0103-1
Publication status	Published - 11.2006

Funding

Acknowledgments Supported by a grant from the Federal Ministry of Education and Research (Fö. 01KS9602) and the Interdisciplinary Center of Clinical Research Tübingen (IZKF). Dr Merseburger is supported by a postgraduate grant from the Novartis Foundation.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Research Area: Luebeck Integrated Oncology Network (LION)

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10.1007/s00345-006-0103-1

Cite this

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title = "Tissue microarrays: Applications in urological cancer research",

abstract = "Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.",

author = "Merseburger, \{A. S.\} and Anastasiadis, \{A. G.\} and J. Hennenlotter and D. Schilling and P. Simon and Machtens, \{S. A.\} and J. Serth and Arnulf Stenzl and Kuczyk, \{Markus A.\}",

note = "Funding Information: Acknowledgments Supported by a grant from the Federal Ministry of Education and Research (F{\"o}. 01KS9602) and the Interdisciplinary Center of Clinical Research T{\"u}bingen (IZKF). Dr Merseburger is supported by a postgraduate grant from the Novartis Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

year = "2006",

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doi = "10.1007/s00345-006-0103-1",

language = "English",

volume = "24",

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T1 - Tissue microarrays: Applications in urological cancer research

AU - Merseburger, A. S.

AU - Anastasiadis, A. G.

AU - Hennenlotter, J.

AU - Schilling, D.

AU - Simon, P.

AU - Machtens, S. A.

AU - Serth, J.

AU - Stenzl, Arnulf

AU - Kuczyk, Markus A.

N1 - Funding Information: Acknowledgments Supported by a grant from the Federal Ministry of Education and Research (Fö. 01KS9602) and the Interdisciplinary Center of Clinical Research Tübingen (IZKF). Dr Merseburger is supported by a postgraduate grant from the Novartis Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

PY - 2006/11

Y1 - 2006/11

N2 - Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.

AB - Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.

UR - https://www.scopus.com/pages/publications/33751238817

U2 - 10.1007/s00345-006-0103-1

DO - 10.1007/s00345-006-0103-1

M3 - Scientific review articles

C2 - 16896596

AN - SCOPUS:33751238817

SN - 0724-4983

VL - 24

SP - 579

EP - 584

JO - World Journal of Urology

JF - World Journal of Urology

IS - 5

ER -

Tissue microarrays: Applications in urological cancer research

Abstract

Funding

UN SDGs

Research Areas and Centers

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