Tissue microarrays: Applications in urological cancer research

A. S. Merseburger, A. G. Anastasiadis, J. Hennenlotter, D. Schilling, P. Simon, S. A. Machtens, J. Serth, Arnulf Stenzl, Markus A. Kuczyk*

*Corresponding author for this work
9 Citations (Scopus)

Abstract

Tissue microarrays (TMAs) are used to simultaneously study the expression of proteins in hundreds of tissue samples, offering the important advantage to screen large tissue banks for biomarker expression and to simultaneously examine serial sections obtained from the same tumor specimen by a time- and cost-effective analytical approach. This review article presents an overview of the importance and the impact of this technique in cancer research with increasing number of investigations using TMAs in its eighth anniversary. Its application, limitations, and selected previous study results regarding urologic malignancies are presented and discussed.

Original languageEnglish
JournalWorld Journal of Urology
Volume24
Issue number5
Pages (from-to)579-584
Number of pages6
ISSN0724-4983
DOIs
Publication statusPublished - 11.2006

Research Areas and Centers

  • Research Area: Luebeck Integrated Oncology Network (LION)

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