Thrombotic thrombocytopenic purpura in metastatic carcinoma of the breast

Nikolas Von Bubnoff, Michael Sandherr, Folker Schneller, Christian Peschel

26 Citations (Scopus)


We present a case of a 52-year-old woman with thrombotic thrombocytopenic purpura associated with progressive metastatic adenocarcinoma of the breast. The patient received plasma exchange therapy. Thrombocytopenic purpura resolved 2 months after discontinuation of plasma exchange while the patient received chemotherapy. After 3 more months, a fulminant relapse of the thrombocytopenic purpura developed, and there were signs of tumor progression. She died despite adequate treatment. We conclude that effective treatment of the underlying tumor can be crucial to control cancer-associated thrombocytopenic purpura.

Original languageEnglish
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Issue number1
Pages (from-to)74-77
Number of pages4
Publication statusPublished - 02.2000


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