Thromboserate und Blutungen in der universitären operativen Urologie unter standardisierter Antikoagulation

Translated title of the contribution: Rate of thrombosis and bleeding after urological surgery under standardized anticoagulation

S. K. Morische, M. W. Kramer, A. S. Merseburger, F. Gieseler, J. Cordes*

*Corresponding author for this work


Background: According to the current definition of the German guideline for prevention of venous thromboembolism, urological surgery includes a high number of high-risk patients. All patients undergoing urological surgery between 2012 and 2016 were analyzed with regard to complications (bleeding or thrombosis). Materials and methods: This study is a retrospective and monocentric cohort study. Included were all patients who underwent surgery between 2012 and 2016 at the Urological Department at the University Hospital of Luebeck. Information was collected relating to anticoagulation, patient-specific and surgery-specific risk factors, and complications. Results: In all, 3609 surgeries were analyzed: 77.8% of patients received no medical prophylaxis, 10.2% received an aggregation inhibitor, and 8.5% synthetic, unfractionated or low molecular weight heparin. Heparin was administered to 80.4% of patients after surgery. During an average hospital stay of 4.5 days, 93.3% of the patients received no change in anticoagulation. Merely 0.8% of all patients suffered from clinical thomboembolic events within 28 days. In contrast the number of bleedings was higher with 20.3% (minor: 4.8%, major: 15.5%). Conclusion: We found a slight risk for postoperative thromboembolism (0.8%). The risk for postoperative bleeding in contrast was 20.3%, including 15.5% major bleedings. The results are discussed in relation to the current guidelines.

Translated title of the contributionRate of thrombosis and bleeding after urological surgery under standardized anticoagulation
Original languageGerman
Issue number1
Pages (from-to)40-51
Number of pages12
Publication statusPublished - 01.01.2020

Research Areas and Centers

  • Research Area: Luebeck Integrated Oncology Network (LION)


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