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Thrombopoietin: The novel hepatic hormone

Eva Maria Wolber*, Wolfgang Jelkmann

*Corresponding author for this work

Abstract

The glycoprotein thrombopoietin (TPO) is the major stimulator of megakaryopoiesis and platelet production. Hepatocytes express TPO mRNA at a constant rate. The plasma TPO level is inversely correlated to the mass of megakaryocytes and platelets, which degrade the hormone following its binding to specific membrane receptors.

Original languageEnglish
JournalNews in Physiological Sciences
Volume17
Issue number1
Pages (from-to)6-10
Number of pages5
ISSN0886-1714
DOIs
Publication statusPublished - 02.2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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