Abstract
The glycoprotein thrombopoietin (TPO) is the major stimulator of megakaryopoiesis and platelet production. Hepatocytes express TPO mRNA at a constant rate. The plasma TPO level is inversely correlated to the mass of megakaryocytes and platelets, which degrade the hormone following its binding to specific membrane receptors.
| Original language | English |
|---|---|
| Journal | News in Physiological Sciences |
| Volume | 17 |
| Issue number | 1 |
| Pages (from-to) | 6-10 |
| Number of pages | 5 |
| ISSN | 0886-1714 |
| DOIs | |
| Publication status | Published - 02.2002 |
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
