Abstract
The glycoprotein thrombopoietin (TPO) is the major stimulator of megakaryopoiesis and platelet production. Hepatocytes express TPO mRNA at a constant rate. The plasma TPO level is inversely correlated to the mass of megakaryocytes and platelets, which degrade the hormone following its binding to specific membrane receptors.
Original language | English |
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Journal | News in Physiological Sciences |
Volume | 17 |
Issue number | 1 |
Pages (from-to) | 6-10 |
Number of pages | 5 |
ISSN | 0886-1714 |
DOIs | |
Publication status | Published - 02.2002 |
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)