Thermo-elastic optical coherence tomography

Tianshi Wang; Tom Pfeiffer; Min Wu; Wolfgang Wieser; Gaetano Amenta; Wolfgang Draxinger; Antonius F.W. Van Der Steen; Robert Huber; Gijs Van Soest

doi:10.1364/OL.42.003466

Thermo-elastic optical coherence tomography

Tianshi Wang, Tom Pfeiffer, Min Wu, Wolfgang Wieser, Gaetano Amenta, Wolfgang Draxinger, Antonius F.W. Van Der Steen, Robert Huber, Gijs Van Soest^*

^*Corresponding author for this work

Institute of Biomedical Optics

Abstract

The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.

Original language	English
Journal	Optics Letters
Volume	42
Issue number	17
Pages (from-to)	3466-3469
Number of pages	4
ISSN	0146-9592
DOIs	https://doi.org/10.1364/OL.42.003466
Publication status	Published - 01.09.2017

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10.1364/OL.42.003466

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abstract = "The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.",

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AU - Wang, Tianshi

AU - Pfeiffer, Tom

AU - Wu, Min

AU - Wieser, Wolfgang

AU - Amenta, Gaetano

AU - Draxinger, Wolfgang

AU - Van Der Steen, Antonius F.W.

AU - Huber, Robert

AU - Van Soest, Gijs

PY - 2017/9/1

Y1 - 2017/9/1

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AB - The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. In this Letter, we investigate the laser-induced thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. A displacement image can be reconstructed, which enables a new modality of phase-sensitive OCT, called thermo-elastic OCT. An analysis of the results shows that the optical absorption is a dominating factor for the displacement. Thermo-elastic OCT is capable of visualizing inclusions that do not appear on the structural OCT image, providing additional tissue type information.

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Thermo-elastic optical coherence tomography

Abstract

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