Therapie der clozapin-induzierten hypersalivation mit botulinum-toxin B

K. G. Kahl; P. Trillenberg; A. Kordon; R. Lencer; C. Klein; J. Hagenah

doi:10.1007/s00115-004-1800-x

Therapie der clozapin-induzierten hypersalivation mit botulinum-toxin B

Translated title of the contribution: Pharmacological strategies for clozapine-induced hypersalivation: Treatment with botulinum toxin B in one patient and review of the literature

K. G. Kahl^*, P. Trillenberg, A. Kordon, R. Lencer, C. Klein, J. Hagenah

^*Corresponding author for this work

6 Citations (Scopus)

Abstract

Hypersalivation is frequently observed in patients treated with clozapine. Current strategies to counteract sialorrhea include the introduction of antimuscarinergic (anticholinergic) and α ₂-agonistic treatment. However, the use of these substances is limited in part by lack of efficacy and by adverse side effects. In cases of intractable sialorrhea, the application of botulinum toxin may be a new and safe therapeutic option. We here present an overview on current treatment strategies for sialorrhea and describe a patient who received botulinum toxin B for clozapine-induced hypersalivation.

Translated title of the contribution	Pharmacological strategies for clozapine-induced hypersalivation: Treatment with botulinum toxin B in one patient and review of the literature
Original language	German
Journal	Nervenarzt
Volume	76
Issue number	2
Pages (from-to)	205-208
Number of pages	4
ISSN	0028-2804
DOIs	https://doi.org/10.1007/s00115-004-1800-x
Publication status	Published - 01.02.2005

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title = "Therapie der clozapin-induzierten hypersalivation mit botulinum-toxin B",

abstract = "Hypersalivation is frequently observed in patients treated with clozapine. Current strategies to counteract sialorrhea include the introduction of antimuscarinergic (anticholinergic) and α 2-agonistic treatment. However, the use of these substances is limited in part by lack of efficacy and by adverse side effects. In cases of intractable sialorrhea, the application of botulinum toxin may be a new and safe therapeutic option. We here present an overview on current treatment strategies for sialorrhea and describe a patient who received botulinum toxin B for clozapine-induced hypersalivation.",

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T1 - Therapie der clozapin-induzierten hypersalivation mit botulinum-toxin B

AU - Kahl, K. G.

AU - Trillenberg, P.

AU - Kordon, A.

AU - Lencer, R.

AU - Klein, C.

AU - Hagenah, J.

PY - 2005/2/1

Y1 - 2005/2/1

N2 - Hypersalivation is frequently observed in patients treated with clozapine. Current strategies to counteract sialorrhea include the introduction of antimuscarinergic (anticholinergic) and α 2-agonistic treatment. However, the use of these substances is limited in part by lack of efficacy and by adverse side effects. In cases of intractable sialorrhea, the application of botulinum toxin may be a new and safe therapeutic option. We here present an overview on current treatment strategies for sialorrhea and describe a patient who received botulinum toxin B for clozapine-induced hypersalivation.

AB - Hypersalivation is frequently observed in patients treated with clozapine. Current strategies to counteract sialorrhea include the introduction of antimuscarinergic (anticholinergic) and α 2-agonistic treatment. However, the use of these substances is limited in part by lack of efficacy and by adverse side effects. In cases of intractable sialorrhea, the application of botulinum toxin may be a new and safe therapeutic option. We here present an overview on current treatment strategies for sialorrhea and describe a patient who received botulinum toxin B for clozapine-induced hypersalivation.

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U2 - 10.1007/s00115-004-1800-x

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SN - 0028-2804

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JO - Nervenarzt

JF - Nervenarzt

IS - 2

ER -

Therapie der clozapin-induzierten hypersalivation mit botulinum-toxin B

Abstract

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