The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study

D. Barthel; C. Otto; S. Nolte; A. K. Meyrose; F. Fischer; J. Devine; O. Walter; A. Mierke; K. I. Fischer; U. Thyen; M. Klein; T. Ankermann; M. Rose; U. Ravens-Sieberer

doi:10.1007/s11136-016-1437-9

The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study

D. Barthel, C. Otto, S. Nolte, A. K. Meyrose, F. Fischer, J. Devine, O. Walter, A. Mierke, K. I. Fischer, U. Thyen, M. Klein, T. Ankermann, M. Rose, U. Ravens-Sieberer^*

^*Corresponding author for this work

20 Citations (Scopus)

Abstract

Purpose: Recently, we developed a computer-adaptive test (CAT) for assessing health-related quality of life (HRQoL) in children and adolescents: the Kids-CAT. It measures five generic HRQoL dimensions. The aims of this article were (1) to present the study design and (2) to investigate its psychometric properties in a clinical setting. Methods: The Kids-CAT study is a longitudinal prospective study with eight measurements over one year at two University Medical Centers in Germany. For validating the Kids-CAT, 270 consecutive 7- to 17-year-old patients with asthma (n = 52), diabetes (n = 182) or juvenile arthritis (n = 36) answered well-established HRQoL instruments (Pediatric Quality of Life Inventory™ (PedsQL), KIDSCREEN-27) and scales measuring related constructs (e.g., social support, self-efficacy). Measurement precision, test–retest reliability, convergent and discriminant validity were investigated. Results: The mean standard error of measurement ranged between.38 and.49 for the five dimensions, which equals a reliability between.86 and.76, respectively. The Kids-CAT measured most reliably in the lower HRQoL range. Convergent validity was supported by moderate to high correlations of the Kids-CAT dimensions with corresponding PedsQL dimensions ranging between.52 and.72. A lower correlation was found between the social dimensions of both instruments. Discriminant validity was confirmed by lower correlations with non-corresponding subscales of the PedsQL. Conclusions: The Kids-CAT measures pediatric HRQoL reliably, particularly in lower areas of HRQoL. Its test–retest reliability should be re-investigated in future studies. The validity of the instrument was demonstrated. Overall, results suggest that the Kids-CAT is a promising candidate for detecting psychosocial needs in chronically ill children.

Original language	English
Journal	Quality of Life Research
Volume	26
Issue number	5
Pages (from-to)	1105-1117
Number of pages	13
ISSN	0962-9343
DOIs	https://doi.org/10.1007/s11136-016-1437-9
Publication status	Published - 01.05.2017

Funding

We thank all children, adolescents and their parents, who participated in the Kids-CAT study. We are grateful to the highly motivated study nurses Anja B?nte and Andrea Knaak and all pediatricians who contributed to the Kids-CAT project. We thank all student assistants and interns for their contributions to data entry and management. We thank the Federal Ministry of Education and Research for funding this research project. The Kids-CAT Study Group comprises: A. B?nte (Department of Pediatrics, University Medical Center Schleswig-Holstein, Campus Kiel, Arnold-Heller-Stra?e 3, House 9, 24105 Kiel, Germany), K. Gulau (Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, Research Unit Child Public Health, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Martinistra?e 52, 20246 Hamburg, Germany), A. Knaak (Hospital for Pediatrics and Adolescent Medicine, University of L?beck, Ratzeburger Allee 160, 23538 L?beck, Germany), H. Muehlan (Department Health & Prevention, Ernst-Moritz-Arndt University; Robert-Blum-Stra?e 13, 17487 Greifswald, Germany), S. Schmidt (Department Health & Prevention, Ernst-Moritz-Arndt University; Robert-Blum-Stra?e 13, 17487 Greifswald, Germany) and S. v. Sengbusch (Hospital for Pediatrics and Adolescent Medicine, University of L?beck, Ratzeburger Allee 160, 23538 L?beck, Germany). This study was funded by the German Federal Ministry of Education and Research (grant number 0010-01GY1111).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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Barthel, D., Otto, C., Nolte, S., Meyrose, A. K., Fischer, F., Devine, J., Walter, O., Mierke, A., Fischer, K. I., Thyen, U., Klein, M., Ankermann, T., Rose, M., & Ravens-Sieberer, U. (2017). The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study. Quality of Life Research, 26(5), 1105-1117. https://doi.org/10.1007/s11136-016-1437-9

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title = "The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study",

abstract = "Purpose: Recently, we developed a computer-adaptive test (CAT) for assessing health-related quality of life (HRQoL) in children and adolescents: the Kids-CAT. It measures five generic HRQoL dimensions. The aims of this article were (1) to present the study design and (2) to investigate its psychometric properties in a clinical setting. Methods: The Kids-CAT study is a longitudinal prospective study with eight measurements over one year at two University Medical Centers in Germany. For validating the Kids-CAT, 270 consecutive 7- to 17-year-old patients with asthma (n = 52), diabetes (n = 182) or juvenile arthritis (n = 36) answered well-established HRQoL instruments (Pediatric Quality of Life Inventory{\texttrademark} (PedsQL), KIDSCREEN-27) and scales measuring related constructs (e.g., social support, self-efficacy). Measurement precision, test–retest reliability, convergent and discriminant validity were investigated. Results: The mean standard error of measurement ranged between.38 and.49 for the five dimensions, which equals a reliability between.86 and.76, respectively. The Kids-CAT measured most reliably in the lower HRQoL range. Convergent validity was supported by moderate to high correlations of the Kids-CAT dimensions with corresponding PedsQL dimensions ranging between.52 and.72. A lower correlation was found between the social dimensions of both instruments. Discriminant validity was confirmed by lower correlations with non-corresponding subscales of the PedsQL. Conclusions: The Kids-CAT measures pediatric HRQoL reliably, particularly in lower areas of HRQoL. Its test–retest reliability should be re-investigated in future studies. The validity of the instrument was demonstrated. Overall, results suggest that the Kids-CAT is a promising candidate for detecting psychosocial needs in chronically ill children.",

author = "D. Barthel and C. Otto and S. Nolte and Meyrose, \{A. K.\} and F. Fischer and J. Devine and O. Walter and A. Mierke and Fischer, \{K. I.\} and U. Thyen and M. Klein and T. Ankermann and M. Rose and U. Ravens-Sieberer",

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month = may,

day = "1",

doi = "10.1007/s11136-016-1437-9",

language = "English",

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pages = "1105--1117",

journal = "Quality of Life Research",

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Barthel, D, Otto, C, Nolte, S, Meyrose, AK, Fischer, F, Devine, J, Walter, O, Mierke, A, Fischer, KI, Thyen, U, Klein, M, Ankermann, T, Rose, M & Ravens-Sieberer, U 2017, 'The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study', Quality of Life Research, vol. 26, no. 5, pp. 1105-1117. https://doi.org/10.1007/s11136-016-1437-9

The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study. / Barthel, D.; Otto, C.; Nolte, S. et al.
In: Quality of Life Research, Vol. 26, No. 5, 01.05.2017, p. 1105-1117.

Research output: Journal Articles › Journal articles › Research › peer-review

TY - JOUR

T1 - The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study

AU - Barthel, D.

AU - Otto, C.

AU - Nolte, S.

AU - Meyrose, A. K.

AU - Fischer, F.

AU - Devine, J.

AU - Walter, O.

AU - Mierke, A.

AU - Fischer, K. I.

AU - Thyen, U.

AU - Klein, M.

AU - Ankermann, T.

AU - Rose, M.

AU - Ravens-Sieberer, U.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Purpose: Recently, we developed a computer-adaptive test (CAT) for assessing health-related quality of life (HRQoL) in children and adolescents: the Kids-CAT. It measures five generic HRQoL dimensions. The aims of this article were (1) to present the study design and (2) to investigate its psychometric properties in a clinical setting. Methods: The Kids-CAT study is a longitudinal prospective study with eight measurements over one year at two University Medical Centers in Germany. For validating the Kids-CAT, 270 consecutive 7- to 17-year-old patients with asthma (n = 52), diabetes (n = 182) or juvenile arthritis (n = 36) answered well-established HRQoL instruments (Pediatric Quality of Life Inventory™ (PedsQL), KIDSCREEN-27) and scales measuring related constructs (e.g., social support, self-efficacy). Measurement precision, test–retest reliability, convergent and discriminant validity were investigated. Results: The mean standard error of measurement ranged between.38 and.49 for the five dimensions, which equals a reliability between.86 and.76, respectively. The Kids-CAT measured most reliably in the lower HRQoL range. Convergent validity was supported by moderate to high correlations of the Kids-CAT dimensions with corresponding PedsQL dimensions ranging between.52 and.72. A lower correlation was found between the social dimensions of both instruments. Discriminant validity was confirmed by lower correlations with non-corresponding subscales of the PedsQL. Conclusions: The Kids-CAT measures pediatric HRQoL reliably, particularly in lower areas of HRQoL. Its test–retest reliability should be re-investigated in future studies. The validity of the instrument was demonstrated. Overall, results suggest that the Kids-CAT is a promising candidate for detecting psychosocial needs in chronically ill children.

AB - Purpose: Recently, we developed a computer-adaptive test (CAT) for assessing health-related quality of life (HRQoL) in children and adolescents: the Kids-CAT. It measures five generic HRQoL dimensions. The aims of this article were (1) to present the study design and (2) to investigate its psychometric properties in a clinical setting. Methods: The Kids-CAT study is a longitudinal prospective study with eight measurements over one year at two University Medical Centers in Germany. For validating the Kids-CAT, 270 consecutive 7- to 17-year-old patients with asthma (n = 52), diabetes (n = 182) or juvenile arthritis (n = 36) answered well-established HRQoL instruments (Pediatric Quality of Life Inventory™ (PedsQL), KIDSCREEN-27) and scales measuring related constructs (e.g., social support, self-efficacy). Measurement precision, test–retest reliability, convergent and discriminant validity were investigated. Results: The mean standard error of measurement ranged between.38 and.49 for the five dimensions, which equals a reliability between.86 and.76, respectively. The Kids-CAT measured most reliably in the lower HRQoL range. Convergent validity was supported by moderate to high correlations of the Kids-CAT dimensions with corresponding PedsQL dimensions ranging between.52 and.72. A lower correlation was found between the social dimensions of both instruments. Discriminant validity was confirmed by lower correlations with non-corresponding subscales of the PedsQL. Conclusions: The Kids-CAT measures pediatric HRQoL reliably, particularly in lower areas of HRQoL. Its test–retest reliability should be re-investigated in future studies. The validity of the instrument was demonstrated. Overall, results suggest that the Kids-CAT is a promising candidate for detecting psychosocial needs in chronically ill children.

UR - https://www.scopus.com/pages/publications/84994465429

U2 - 10.1007/s11136-016-1437-9

DO - 10.1007/s11136-016-1437-9

M3 - Journal articles

C2 - 27830512

AN - SCOPUS:84994465429

SN - 0962-9343

VL - 26

SP - 1105

EP - 1117

JO - Quality of Life Research

JF - Quality of Life Research

IS - 5

ER -

The validation of a computer-adaptive test (CAT) for assessing health-related quality of life in children and adolescents in a clinical sample: study design, methods and first results of the Kids-CAT study

Abstract

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