The Telomeric Complex and Metabolic Disease

Henriette Kirchner, Fozia Shaheen, Hannes Kalscheuer, Sebastian M. Schmid, Henrik Oster, Hendrik Lehnert*

*Corresponding author for this work
5 Citations (Scopus)


The attrition of telomeres is believed to be a key event not only in mammalian aging, but also in disturbed nutrient sensing, which could lead to numerous metabolic dysfunctions. The current debate focuses mainly on the question whether telomere shortening, e.g., as a heritable trait, may act as a cause or rather represents a consequence of such chronic diseases. This review discusses the damaging events that ultimately may lead or contribute to telomere shortening and can be associated with metabolic diseases.

Original languageEnglish
Article number176
Issue number7
Publication statusPublished - 07.07.2017

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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