The sooner, the later – Delayed diagnosis in Parkinson's disease due to Parkin mutations

Max Borsche; Alexander Balck; Meike Kasten; Katja Lohmann; Christine Klein; Norbert Brüggemann

doi:10.1016/j.parkreldis.2019.06.020

The sooner, the later – Delayed diagnosis in Parkinson's disease due to Parkin mutations

Max Borsche, Alexander Balck, Meike Kasten, Katja Lohmann, Christine Klein, Norbert Brüggemann^*

^*Corresponding author for this work

7 Citations (Scopus)

Abstract

The diagnosis of Parkinson's disease (PD) in patients carrying mutations in the Parkin gene is frequently delayed. We confirmed this finding in a sample of nine biallelic Parkin-PD patients with a mean delay of nine years and found an inverse relationship between diagnostic delay and age at onset.

Original language	English
Journal	Parkinsonism and Related Disorders
Volume	65
Pages (from-to)	284-285
Number of pages	2
ISSN	1353-8020
DOIs	https://doi.org/10.1016/j.parkreldis.2019.06.020
Publication status	Published - 08.2019

Funding

The study was supported by funding from the SysMedPD project from the European Union’s Horizon 2020 research and innovation program under grant agreement No. 668738 and by EU grant GENEPARK (EU-LSHB-CT- 2006-037544 ). AB has received funding by the University of Lübeck through a career development award. NB, MK, KL and CK are supported by the DFG ( FOR2488 ).

Research Areas and Centers

Research Area: Medical Genetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.parkreldis.2019.06.020

Cite this

@article{ce007c3737ec4456bfb5221269b8a2e0,

title = "The sooner, the later – Delayed diagnosis in Parkinson's disease due to Parkin mutations",

abstract = "The diagnosis of Parkinson's disease (PD) in patients carrying mutations in the Parkin gene is frequently delayed. We confirmed this finding in a sample of nine biallelic Parkin-PD patients with a mean delay of nine years and found an inverse relationship between diagnostic delay and age at onset.",

author = "Max Borsche and Alexander Balck and Meike Kasten and Katja Lohmann and Christine Klein and Norbert Br{\"u}ggemann",

year = "2019",

month = aug,

doi = "10.1016/j.parkreldis.2019.06.020",

language = "English",

volume = "65",

pages = "284--285",

journal = "Parkinsonism and Related Disorders",

issn = "1353-8020",

publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - The sooner, the later – Delayed diagnosis in Parkinson's disease due to Parkin mutations

AU - Borsche, Max

AU - Balck, Alexander

AU - Kasten, Meike

AU - Lohmann, Katja

AU - Klein, Christine

AU - Brüggemann, Norbert

PY - 2019/8

Y1 - 2019/8

N2 - The diagnosis of Parkinson's disease (PD) in patients carrying mutations in the Parkin gene is frequently delayed. We confirmed this finding in a sample of nine biallelic Parkin-PD patients with a mean delay of nine years and found an inverse relationship between diagnostic delay and age at onset.

AB - The diagnosis of Parkinson's disease (PD) in patients carrying mutations in the Parkin gene is frequently delayed. We confirmed this finding in a sample of nine biallelic Parkin-PD patients with a mean delay of nine years and found an inverse relationship between diagnostic delay and age at onset.

UR - https://www.scopus.com/pages/publications/85072722523

U2 - 10.1016/j.parkreldis.2019.06.020

DO - 10.1016/j.parkreldis.2019.06.020

M3 - Letters

C2 - 31255538

AN - SCOPUS:85072722523

SN - 1353-8020

VL - 65

SP - 284

EP - 285

JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

ER -

The sooner, the later – Delayed diagnosis in Parkinson's disease due to Parkin mutations

Abstract

Funding

Research Areas and Centers

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this