The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD + AML but retains in vitro sensitivity to PKC412 and Sunitinib

C. Albers; H. Leischner; M. Verbeek; C. Yu; A. L. Illert; C. Peschel; N. Von Bubnoff; J. Duyster

doi:10.1038/leu.2013.14

The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD + AML but retains in vitro sensitivity to PKC412 and Sunitinib

C. Albers, H. Leischner, M. Verbeek, C. Yu, A. L. Illert, C. Peschel, N. Von Bubnoff, J. Duyster

Clinic of Hematology and Oncology

Original language	English
Journal	Leukemia
Volume	27
Issue number	6
Pages (from-to)	1416-1418
Number of pages	3
ISSN	0887-6924
DOIs	https://doi.org/10.1038/leu.2013.14
Publication status	Published - 06.2013

Funding

This work was supported by grants from the National Council of Scientific and Technical Research (CONICET; Argentina), National Agency for Promotion of Science and Technology (Argentina), University of Buenos Aires and Fundación Sales (Argentina).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/leu.2013.14

Cite this

@article{dc2df99a34584aabac9317616318454a,

title = "The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD + AML but retains in vitro sensitivity to PKC412 and Sunitinib",

author = "C. Albers and H. Leischner and M. Verbeek and C. Yu and Illert, \{A. L.\} and C. Peschel and \{Von Bubnoff\}, N. and J. Duyster",

note = "Funding Information: This work was supported by grants from the National Council of Scientific and Technical Research (CONICET; Argentina), National Agency for Promotion of Science and Technology (Argentina), University of Buenos Aires and Fundaci{\'o}n Sales (Argentina).",

year = "2013",

month = jun,

doi = "10.1038/leu.2013.14",

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T1 - The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD + AML but retains in vitro sensitivity to PKC412 and Sunitinib

AU - Albers, C.

AU - Leischner, H.

AU - Verbeek, M.

AU - Yu, C.

AU - Illert, A. L.

AU - Peschel, C.

AU - Von Bubnoff, N.

AU - Duyster, J.

N1 - Funding Information: This work was supported by grants from the National Council of Scientific and Technical Research (CONICET; Argentina), National Agency for Promotion of Science and Technology (Argentina), University of Buenos Aires and Fundación Sales (Argentina).

PY - 2013/6

Y1 - 2013/6

UR - https://www.scopus.com/pages/publications/84878916655

U2 - 10.1038/leu.2013.14

DO - 10.1038/leu.2013.14

M3 - Letters

C2 - 23392356

AN - SCOPUS:84878916655

SN - 0887-6924

VL - 27

SP - 1416

EP - 1418

JO - Leukemia

JF - Leukemia

IS - 6

ER -

The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD + AML but retains in vitro sensitivity to PKC412 and Sunitinib

Funding

UN SDGs

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