The role of long-lived plasma cells in autoimmunity review

Sergio Arce, Giuliana Cassese, Anja Hauser, Thomas Dörner, Marcus Odendahl, Rudi Manz, Andreas Radbruch, Falk Hiepe

18 Citations (Scopus)


Recent results on the biology of plasma cells have shown that these cells can survive as long as memory B cells. Possibly, such long-lived plasma cells are also involved in the production of autoantibodies. Here, we discuss the potential involvement of long-lived plasma cells in the pathogenesis of autoimmune disease and the consequences it has for the development of effective therapeutic strategies.

Original languageEnglish
Issue number5
Pages (from-to)558-562
Number of pages5
Publication statusPublished - 12.2002


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