The potential of ribozymes as antiviral agents

G. Sczakiel*, W. Nedbal

*Corresponding author for this work
17 Citations (Scopus)

Abstract

Ribozymes are promising tools for the specific inhibition of viral gene expression and replication. They represent one of the most attractive developments of antisense nucleic acids, which have been shown in the past few years to act as antiviral agents. Ribozymes not only complex with target sequences via complementary antisense sequences, but also hydrolyze the target site.

Original languageEnglish
JournalTrends in Microbiology
Volume3
Issue number6
Pages (from-to)213-217
Number of pages5
ISSN0966-842X
DOIs
Publication statusPublished - 06.1995

Funding

We apologizeto the authorso f all the excellent publicariontsh atcould not be cited here due to space limitations. We wish to thank H. zur Hausen for his continuous support. This laboratory was supported by grants from the European Union, the Deutsche Forschungsgemeinschaft and the Bundesministerium fiir Forschung und Technologie.

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