The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task

ICCAM Consortium; MTAC

doi:10.1007/s11065-018-9385-5

The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task

ICCAM Consortium, MTAC

Clinic of Psychiatry and Psychotherapy

148 Citations (Scopus)

Abstract

The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.

Original language	English
Journal	Neuropsychology Review
Volume	28
Issue number	4
ISSN	1040-7308
DOIs	https://doi.org/10.1007/s11065-018-9385-5
Publication status	Published - 15.12.2018

Funding

We would like to acknowledge the support of Joaquim Radua, Anton Albajes-Eizagirre, Christian Windischberger and Rupert Lanzenberger. Monetary Incentive Delay Task Analysis Consortium (MTAC) (arranged in alphabetical order): Abe, N, Barros-Loscertales, AR, Bayer, J, Beck, A, Bjork, J, Boecker, R, Bustamante, JC, Choi, JS, Delmonte, S, Dillon, D, Figee, M, Garavan, H, Hagele, C, Hermans, EJ, ICCAM Consortium, Ikeda, Y, Kappel, V, Kaufmann, C, Lamm, C, Lammertz, SE, Li, Y, Murphy, A, Nestor, L, Pecina, M, Pfabigan, D, Pizzagalli, D, Rademacher L, Admon, R, Sommer T, Stark, R, Suzuki, H, Van Amelsvoort, T, Van Hell, E, Vink M, Votinov, M, Wotruba, D. Acknowledgements We would like to acknowledge the support of Joaquim Radua, Anton Albajes-Eizagirre, Christian Windischberger and Rupert Lanzenberger.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

Access to Document

10.1007/s11065-018-9385-5

Cite this

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title = "The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task",

abstract = "The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.",

author = "\{ICCAM Consortium\} and MTAC and Wilson, \{Robin Paul\} and Marco Colizzi and Bossong, \{Matthijs Geert\} and Paul Allen and Matthew Kempton and N. Abe and Barros-Loscertales, \{A. R.\} and J. Bayer and A. Beck and J. Bjork and R. Boecker and Bustamante, \{J. C.\} and Choi, \{J. S.\} and S. Delmonte and D. Dillon and M. Figee and H. Garavan and C. Hagele and Hermans, \{E. J.\} and Y. Ikeda and V. Kappel and C. Kaufmann and C. Lamm and Lammertz, \{S. E.\} and Y. Li and A. Murphy and L. Nestor and M. Pecina and D. Pfabigan and D. Pizzagalli and L. Rademacher and R. Admon and T. Sommer and R. Stark and H. Suzuki and \{Van Amelsvoort\}, T. and \{Van Hell\}, E. and M. Vink and M. Votinov and D. Wotruba and Sagnik Bhattacharyya",

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doi = "10.1007/s11065-018-9385-5",

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AU - ICCAM Consortium

AU - MTAC

AU - Wilson, Robin Paul

AU - Colizzi, Marco

AU - Bossong, Matthijs Geert

AU - Allen, Paul

AU - Kempton, Matthew

AU - Abe, N.

AU - Barros-Loscertales, A. R.

AU - Bayer, J.

AU - Beck, A.

AU - Bjork, J.

AU - Boecker, R.

AU - Bustamante, J. C.

AU - Choi, J. S.

AU - Delmonte, S.

AU - Dillon, D.

AU - Figee, M.

AU - Garavan, H.

AU - Hagele, C.

AU - Hermans, E. J.

AU - Ikeda, Y.

AU - Kappel, V.

AU - Kaufmann, C.

AU - Lamm, C.

AU - Lammertz, S. E.

AU - Li, Y.

AU - Murphy, A.

AU - Nestor, L.

AU - Pecina, M.

AU - Pfabigan, D.

AU - Pizzagalli, D.

AU - Rademacher, L.

AU - Admon, R.

AU - Sommer, T.

AU - Stark, R.

AU - Suzuki, H.

AU - Van Amelsvoort, T.

AU - Van Hell, E.

AU - Vink, M.

AU - Votinov, M.

AU - Wotruba, D.

AU - Bhattacharyya, Sagnik

PY - 2018/12/15

Y1 - 2018/12/15

N2 - The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.

AB - The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.

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SN - 1040-7308

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JO - Neuropsychology Review

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IS - 4

ER -

The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task

Abstract

Funding

UN SDGs

Research Areas and Centers

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