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The Human Affectome

  • Daniela Schiller*
  • , Alessandra N.C. Yu
  • , Nelly Alia-Klein
  • , Susanne Becker
  • , Howard C. Cromwell
  • , Florin Dolcos
  • , Paul J. Eslinger
  • , Paul Frewen
  • , Andrew H. Kemp
  • , Edward F. Pace-Schott
  • , Jacob Raber
  • , Rebecca L. Silton
  • , Elka Stefanova
  • , Justin H.G. Williams
  • , Nobuhito Abe
  • , Moji Aghajani
  • , Franziska Albrecht
  • , Rebecca Alexander
  • , Silke Anders
  • , Oriana R. Aragón
  • Juan A. Arias, Shahar Arzy, Tatjana Aue, Sandra Baez, Michela Balconi, Tommaso Ballarini, Scott Bannister, Marlissa C. Banta, Karen Caplovitz Barrett, Catherine Belzung, Moustafa Bensafi, Linda Booij, Jamila Bookwala, Julie Boulanger-Bertolus, Sydney Weber Boutros, Anne Kathrin Bräscher, Antonio Bruno, Geraldo Busatto, Lauren M. Bylsma, Catherine Caldwell-Harris, Raymond C.K. Chan, Nicolas Cherbuin, Julian Chiarella, Pietro Cipresso, Hugo Critchley, Denise E. Croote, Heath A. Demaree, Thomas F. Denson, Brendan Depue, Birgit Derntl, Joanne M. Dickson, Sanda Dolcos, Anat Drach-Zahavy, Olga Dubljević, Tuomas Eerola, Dan Mikael Ellingsen, Beth Fairfield, Camille Ferdenzi, Bruce H. Friedman, Cynthia H.Y. Fu, Justine M. Gatt, Beatrice de Gelder, Guido H.E. Gendolla, Gadi Gilam, Hadass Goldblatt, Anne Elizabeth Kotynski Gooding, Olivia Gosseries, Alfons O. Hamm, Jamie L. Hanson, Talma Hendler, Cornelia Herbert, Stefan G. Hofmann, Agustin Ibanez, Mateus Joffily, Tanja Jovanovic, Ian J. Kahrilas, Maria Kangas, Yuta Katsumi, Elizabeth Kensinger, Lauren A.J. Kirby, Rebecca Koncz, Ernst H.W. Koster, Kasia Kozlowska, Sören Krach, Mariska E. Kret, Martin Krippl, Kwabena Kusi-Mensah, Cecile D. Ladouceur, Steven Laureys, Alistair Lawrence, Chiang shan R. Li, Belinda J. Liddell, Navdeep K. Lidhar, Christopher A. Lowry, Kelsey Magee, Marie France Marin, Veronica Mariotti, Loren J. Martin, Hilary A. Marusak, Annalina V. Mayer, Amanda R. Merner, Jessica Minnier, Jorge Moll, Robert G. Morrison, Matthew Moore, Anne Marie Mouly, Sven C. Mueller, Andreas Mühlberger, Nora A. Murphy, Maria Rosaria Anna Muscatello, Erica D. Musser, Tamara L. Newton, Michael Noll-Hussong, Seth Davin Norrholm, Georg Northoff, Robin Nusslock, Hadas Okon-Singer, Thomas M. Olino, Catherine Ortner, Mayowa Owolabi, Caterina Padulo, Romina Palermo, Rocco Palumbo, Sara Palumbo, Christos Papadelis, Alan J. Pegna, Silvia Pellegrini, Kirsi Peltonen, Brenda W.J.H. Penninx, Pietro Pietrini, Graziano Pinna, Rosario Pintos Lobo, Kelly L. Polnaszek, Maryna Polyakova, Christine Rabinak, S. Helene Richter, Thalia Richter, Giuseppe Riva, Amelia Rizzo, Jennifer L. Robinson, Pedro Rosa, Perminder S. Sachdev, Wataru Sato, Matthias L. Schroeter, Susanne Schweizer, Youssef Shiban, Advaith Siddharthan, Ewa Siedlecka, Robert C. Smith, Hermona Soreq, Derek P. Spangler, Emily R. Stern, Charis Styliadis, Gavin B. Sullivan, James E. Swain, Sébastien Urben, Jan Van den Stock, Michael A. vander Kooij, Mark van Overveld, Tamsyn E. Van Rheenen, Michael B. VanElzakker, Carlos Ventura-Bort, Edelyn Verona, Tyler Volk, Yi Wang, Leah T. Weingast, Mathias Weymar, Claire Williams, Megan L. Willis, Paula Yamashita, Roland Zahn, Barbra Zupan, Leroy Lowe*
*Corresponding author for this work
  • Mount Sinai School of Medicine
  • Medical Faculty Mannheim/ Heidelberg University
  • Balgrist University Hospital
  • Bowling Green State University
  • University of Illinois at Urbana-Champaign
  • Pennsylvania State University
  • University of Western Ontario
  • Swansea University
  • Harvard University
  • Oregon Health & Science University
  • Loyola University Chicago
  • University of Belgrade
  • Clinical Center of Serbia
  • Griffith University
  • Kyoto University
  • Leiden University
  • Amsterdam Neuroscience
  • Max Planck Institute for Human Cognitive and Brain Research
  • University of Leipzig
  • Karolinska Institutet
  • Neuroscience Research Australia
  • Australian National University
  • Yale University
  • University of Cincinnati
  • University Santiago de Compostela
  • The Galician Center for Mathematical Research and Technology (CITMAga)
  • Hebrew University of Jerusalem
  • University of Bern
  • University of Los Andes
  • Universita' Cattolica del Sacro Cuore sede Piacenza
  • Duke University
  • VA Medical Center
  • Colorado State University
  • Colorado School of Public Health
  • Université de Tours
  • Centre de Recherche en Neurosciences de Lyon
  • Concordia University
  • CHU Sainte-Justine - Le centre hospitalier universitaire mere-enfant
  • Lafayette College
  • University of Michigan
  • Johannes Gutenberg University Mainz
  • Nathan S. Kline Institute for Psychiatric Research
  • University of Messina
  • University of Sao Paulo
  • University of Pittsburgh School of Medicine
  • Boston University School of Medicine
  • Chinese Academy of Sciences
  • IRCCS Istituto Auxologico Italiano - Milano
  • University of Turin
  • University of Sussex
  • Universidade do Rio de Janeiro
  • Case Western Reserve University School of Medicine
  • Macquarie University, Australian School of Advanced Medicine
  • University of Louisville School of Medicine
  • University of Tubingen
  • Edith Cowan University
  • University of Haifa
  • University of Oslo
  • Federico II University
  • UniCamillus - Saint Camillus International University of Health and Medical Sciences
  • Virginia Polytechnic Institute and State University
  • Polytechnic of East London
  • King's College London
  • Maastricht University
  • University of Geneva
  • Stanford University
  • University Hospital of Liège
  • University of Greifswald
  • University of Pittsburgh
  • Tel-Aviv University
  • University of Ulm
  • University of Marburg
  • Universidad de San Andres
  • Universidad Nacional de La Plata
  • Universidad Adolfo Ibáñez
  • University of California San Francisco
  • Groupe d'Analyse et de Théorie Economique (GATE)
  • Wayne State University
  • Macquarie University
  • Boston College
  • University of Texas at Tyler
  • University of Sydney
  • Ghent University
  • Otto von Guericke University Magdeburg
  • Komfo Anokye Teaching Hospital
  • Department of Psychiatry
  • Kwame Nkrumah University of Science and Technology
  • Scotland's Rural College
  • Roslin Institute
  • Yale University School of Medicine
  • University Health Network
  • University of Colorado Boulder
  • Université du Québec à Montréal
  • Institut universitaire en santé mentale de Montréal
  • University of Pisa
  • D’Or Institute for Research and Education
  • Department of Veterans Affairs Palo Alto Healthcare System
  • University of Regensburg
  • Loyola Marymount University
  • Florida International University
  • University of Louisville
  • Technical University of Munich
  • Royal Ottawa Mental Health Centre
  • Northwestern University
  • Temple University
  • Thompson Rivers University
  • College of Medicine, University of Ibadan
  • Blossom Specialist Medical Center
  • Gabriele D'Annunzio University of Chieti-Pescara
  • University of Western Australia
  • Cook Children's Health Care System
  • University of Texas at Arlington College of Engineering
  • The University of Queensland
  • University of Turku
  • IMT Institute for Advanced Studies Lucca
  • University of Illinois at Chicago
  • University of Münster
  • Auburn University
  • Prince of Wales Hospital
  • RIKEN Center for Integrative Medical Science
  • University of Cambridge
  • PFH – Private University of Applied Sciences
  • Open University
  • Michigan State University
  • Columbia University in the City of New York
  • Aristotle University of Thessaloniki, Greece.
  • International Psychoanalytic University
  • Stony Brook University
  • University of Lausanne
  • KU Leuven
  • Erasmus University Medical Center
  • University of Melbourne
  • Universität Potsdam
  • University of South Florida Tampa
  • New York University
  • Kennesaw State University
  • The Avalon Centre
  • Australian Catholic University
  • Central Queensland University
  • Neuroqualia (NGO)

Abstract

Over the last decades, theoretical perspectives in the interdisciplinary field of the affective sciences have proliferated rather than converged due to differing assumptions about what human affective phenomena are and how they work. These metaphysical and mechanistic assumptions, shaped by academic context and values, have dictated affective constructs and operationalizations. However, an assumption about the purpose of affective phenomena can guide us to a common set of metaphysical and mechanistic assumptions. In this capstone paper, we home in on a nested teleological principle for human affective phenomena in order to synthesize metaphysical and mechanistic assumptions. Under this framework, human affective phenomena can collectively be considered algorithms that either adjust based on the human comfort zone (affective concerns) or monitor those adaptive processes (affective features). This teleologically-grounded framework offers a principled agenda and launchpad for both organizing existing perspectives and generating new ones. Ultimately, we hope the Human Affectome brings us a step closer to not only an integrated understanding of human affective phenomena, but an integrated field for affective research.

Original languageEnglish
Article number105450
JournalNeuroscience and Biobehavioral Reviews
Volume158
Pages (from-to)105450
ISSN0149-7634
DOIs
Publication statusPublished - 03.2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

DFG Research Classification Scheme

  • 1.22-02 Biological Psychology and Cognitive Neurosciences
  • 2.23-09 Biological Psychiatry

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