The genetic basis of circadian behavior

H. Oster*

*Corresponding author for this work
23 Citations (Scopus)


In most species, an endogenous timing system synchronizes physiology and behavior to the rhythmic succession of day and night. The mammalian circadian pacemaker residing in the suprachiasmatic nuclei (SCN) of the hypothalamus controls peripheral clocks throughout the brain and the body via humoral and neuronal transmission. On the cellular level, these clockworks consist of a set of interwoven transcriptional/translational feedback loops. Recent work emphasizes the tissue specificity of some components of these molecular clockworks and the differential regulation of their rhythmicity by the SCN.

Original languageEnglish
JournalGenes, Brain and Behavior
Issue numberSUPPL. 2
Pages (from-to)73-79
Number of pages7
Publication statusPublished - 06.2006

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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