Temporal trends in fetal mortality at and beyond term and induction of labor in Germany 2005–2012: data from German routine perinatal monitoring

Christiane Schwarz*, Rainhild Schäfers, Christine Loytved, Peter Heusser, Michael Abou-Dakn, Thomas König, Bettina Berger

*Corresponding author for this work
5 Citations (Scopus)

Abstract

Purpose: While a variety of factors may play a role in fetal and neonatal deaths, postmaturity as a cause of stillbirth remains a topic of debate. It still is unclear, whether induction of labor at a particular gestational age may prevent fetal deaths. Methods: A multidisciplinary working group was granted access to the most recent set of relevant German routine perinatal data, comprising all 5,291,011 hospital births from 2005 to 2012. We analyzed correlations in rates of induction of labor (IOL), perinatal mortality (in particular stillbirths) at different gestational ages, and fetal morbidity. Correlations were tested with Pearson’s product-moment analysis (α = 5 %). All computations were performed with SPSS version 22. Results: Induction rates rose significantly from 16.5 to 21.9 % (r = 0.98; p < 0.001). There were no significant changes in stillbirth rates (0.28–0.35 per 100 births; r = 0.045; p = 0.806). Stillbirth rates 2009–2012 remained stable in all gestational age groups irrespective of induction. Fetal morbidity (one or more ICD-10 codes) rose significantly during 2005–2012. This was true for both children with (from 33 to 37 %, r = 0.784, p < 0.001) and without (from 25 to 31 %, (r = 0.920, p < 0.001) IOL. Conclusions: An increase in IOL at term is not associated with a decline in perinatal mortality. Perinatal morbidity increased with and without indiction of labor.

Original languageEnglish
JournalArchives of Gynecology and Obstetrics
Volume293
Issue number2
Pages (from-to)335-343
Number of pages9
ISSN0932-0067
DOIs
Publication statusPublished - 01.02.2016

Research Areas and Centers

  • Health Sciences

DFG Research Classification Scheme

  • 2.22-02 Public Health, Healthcare Research, Social and Occupational Medicine
  • 2.22-21 Gynaecology and Obstetrics

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