Abstract
CD4+NKG2D+effector memory T-cell-mediated endothelial cell damage and a Th17 dominated cytokine profile of PR3-specific T-cells may play an important role in the pathogenesis of granulomatosis with polyangiitis (Wegener's). The anti-IL-5 antibody mepolizumab (anti-IL-5) induces remission in Churg-Strauss syndrome.
| Translated title of the contribution | T-cells in ANCA-associated vasculitis |
|---|---|
| Original language | German |
| Journal | Zeitschrift fur Rheumatologie |
| Volume | 70 |
| Issue number | 8 |
| Pages (from-to) | 698-700 |
| Number of pages | 3 |
| ISSN | 0340-1855 |
| DOIs | |
| Publication status | Published - 10.2011 |
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)
