Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Olaf Wolkenhauer; Charles Auffray; Simone Baltrusch; Nils Blüthgen; Helen Byrne; Marta Cascante; Andrea Ciliberto; Trevor Dale; Dirk Drasdo; David Fell; James E. Ferrell; Daniel Gallahan; Robert Gatenby; Ulrich Günther; Brian D. Harms; Hanspeter Herzel; Christian Junghanss; Manfred Kunz; Ingeborg Van Leeuwen; Philippe Lenormand; Francis Levi; Michael Linnebacher; John Lowengrub; Philip K. Maini; Arif Malik; Katja Rateitschak; Owen Sansom; Reinhold Schäfer; Karsten Schürrle; Christine Sers; Santiago Schnell; Darryl Shibata; John Tyson; Julio Vera; Michael White; Boris Zhivotovsky; Robert Jaster

doi:10.1158/0008-5472.CAN-09-2676

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Olaf Wolkenhauer^*, Charles Auffray, Simone Baltrusch, Nils Blüthgen, Helen Byrne, Marta Cascante, Andrea Ciliberto, Trevor Dale, Dirk Drasdo, David Fell, James E. Ferrell, Daniel Gallahan, Robert Gatenby, Ulrich Günther, Brian D. Harms, Hanspeter Herzel, Christian Junghanss, Manfred Kunz, Ingeborg Van Leeuwen, Philippe LenormandFrancis Levi, Michael Linnebacher, John Lowengrub, Philip K. Maini, Arif Malik, Katja Rateitschak, Owen Sansom, Reinhold Schäfer, Karsten Schürrle, Christine Sers, Santiago Schnell, Darryl Shibata, John Tyson, Julio Vera, Michael White, Boris Zhivotovsky, Robert Jaster

^*Corresponding author for this work

36 Citations (Scopus)

Abstract

Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.

Original language	English
Journal	Cancer Research
Volume	70
Issue number	1
Pages (from-to)	12-13
Number of pages	2
ISSN	0008-5472
DOIs	https://doi.org/10.1158/0008-5472.CAN-09-2676
Publication status	Published - 01.01.2010

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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10.1158/0008-5472.CAN-09-2676

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Wolkenhauer, O., Auffray, C., Baltrusch, S., Blüthgen, N., Byrne, H., Cascante, M., Ciliberto, A., Dale, T., Drasdo, D., Fell, D., Ferrell, J. E., Gallahan, D., Gatenby, R., Günther, U., Harms, B. D., Herzel, H., Junghanss, C., Kunz, M., Van Leeuwen, I., ... Jaster, R. (2010). Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Research, 70(1), 12-13. https://doi.org/10.1158/0008-5472.CAN-09-2676

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title = "Systems biologists seek fuller integration of systems biology approaches in new cancer research programs",

abstract = "Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.",

author = "Olaf Wolkenhauer and Charles Auffray and Simone Baltrusch and Nils Bl{\"u}thgen and Helen Byrne and Marta Cascante and Andrea Ciliberto and Trevor Dale and Dirk Drasdo and David Fell and Ferrell, \{James E.\} and Daniel Gallahan and Robert Gatenby and Ulrich G{\"u}nther and Harms, \{Brian D.\} and Hanspeter Herzel and Christian Junghanss and Manfred Kunz and \{Van Leeuwen\}, Ingeborg and Philippe Lenormand and Francis Levi and Michael Linnebacher and John Lowengrub and Maini, \{Philip K.\} and Arif Malik and Katja Rateitschak and Owen Sansom and Reinhold Sch{\"a}fer and Karsten Sch{\"u}rrle and Christine Sers and Santiago Schnell and Darryl Shibata and John Tyson and Julio Vera and Michael White and Boris Zhivotovsky and Robert Jaster",

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doi = "10.1158/0008-5472.CAN-09-2676",

language = "English",

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Wolkenhauer, O, Auffray, C, Baltrusch, S, Blüthgen, N, Byrne, H, Cascante, M, Ciliberto, A, Dale, T, Drasdo, D, Fell, D, Ferrell, JE, Gallahan, D, Gatenby, R, Günther, U, Harms, BD, Herzel, H, Junghanss, C, Kunz, M, Van Leeuwen, I, Lenormand, P, Levi, F, Linnebacher, M, Lowengrub, J, Maini, PK, Malik, A, Rateitschak, K, Sansom, O, Schäfer, R, Schürrle, K, Sers, C, Schnell, S, Shibata, D, Tyson, J, Vera, J, White, M, Zhivotovsky, B & Jaster, R 2010, 'Systems biologists seek fuller integration of systems biology approaches in new cancer research programs', Cancer Research, vol. 70, no. 1, pp. 12-13. https://doi.org/10.1158/0008-5472.CAN-09-2676

TY - JOUR

T1 - Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

AU - Wolkenhauer, Olaf

AU - Auffray, Charles

AU - Baltrusch, Simone

AU - Blüthgen, Nils

AU - Byrne, Helen

AU - Cascante, Marta

AU - Ciliberto, Andrea

AU - Dale, Trevor

AU - Drasdo, Dirk

AU - Fell, David

AU - Ferrell, James E.

AU - Gallahan, Daniel

AU - Gatenby, Robert

AU - Günther, Ulrich

AU - Harms, Brian D.

AU - Herzel, Hanspeter

AU - Junghanss, Christian

AU - Kunz, Manfred

AU - Van Leeuwen, Ingeborg

AU - Lenormand, Philippe

AU - Levi, Francis

AU - Linnebacher, Michael

AU - Lowengrub, John

AU - Maini, Philip K.

AU - Malik, Arif

AU - Rateitschak, Katja

AU - Sansom, Owen

AU - Schäfer, Reinhold

AU - Schürrle, Karsten

AU - Sers, Christine

AU - Schnell, Santiago

AU - Shibata, Darryl

AU - Tyson, John

AU - Vera, Julio

AU - White, Michael

AU - Zhivotovsky, Boris

AU - Jaster, Robert

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.

AB - Systems biology takes an interdisciplinary approach to the systematic study of complex interactions in biological systems. This approach seeks to decipher the emergent behaviors of complex systems rather than focusing only on their constituent properties. As an increasing number of examples illustrate the value of systems biology approaches to understand the initiation, progression, and treatment of cancer, systems biologists from across Europe and the United States hope for changes in the way their field is currently perceived among cancer researchers. In a recent EU-US workshop, supported by the European Commission, the German Federal Ministry for Education and Research, and the National Cancer Institute of the NIH, the participants discussed the strengths, weaknesses, hurdles, and opportunities in cancer systems biology.

UR - https://www.scopus.com/pages/publications/75149188853

U2 - 10.1158/0008-5472.CAN-09-2676

DO - 10.1158/0008-5472.CAN-09-2676

M3 - Journal articles

C2 - 20028868

AN - SCOPUS:75149188853

SN - 0008-5472

VL - 70

SP - 12

EP - 13

JO - Cancer Research

JF - Cancer Research

IS - 1

ER -

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Abstract

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