Systemische Sklerose

Translated title of the contribution: Systemic sclerosis

Susanne Schinke*, Gabriela Riemekasten

*Corresponding author for this work


Systemic sclerosis (SSc) is a rare fibrosing rheumatic multi-systemic disease involving many medical specialties. The mortality of SSc is determined by lung fibrosis, pulmonary arterial hypertension and cardiac involvement. With early and intensive treatment, the disease can be stabilized and symptoms relieved. This review summarizes insights into pathophysiology, disease classification, clinical manifestations and successful therapies, as well as recent studies on new immunosuppressant, biological and vasoactive therapies.

Translated title of the contributionSystemic sclerosis
Original languageGerman
Issue number12
Pages (from-to)1251-1269
Number of pages19
Publication statusPublished - 01.12.2019

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)
  • Centers: Center for Rare Diseases (ZSE)

DFG Research Classification Scheme

  • 205-18 Rheumatology


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