Systemic sclerosis - A systematic overview: Part 1 - Disease characteristics and classification, pathophysiologic concepts, and recommendations for diagnosis and surveillance

Peter Klein-Weigel*, C. Opitz, G. Riemekasten

*Corresponding author for this work
21 Citations (Scopus)

Abstract

Due to its high association with Raynaud's phenomenon systemic sclerosis (SSc) is probably the most common connective tissue disease seen by vascular specialists. In part 1 of our systematic overview we summarize classification concepts of scleroderma disorders, the epidemiologic and genetic burden, the complex pathophysiologic background, and the clinical features and the stage-dependent capillary microscopic features of SSc. Furthermore, we address the diagnostic recommendations propagated by the German Network for Systemic Sclerosis and the Task Force for Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology, the European Respiratory Society, and the International Society of Heart and Lung Transplantation.

Original languageEnglish
JournalVasa - Journal of Vascular Diseases
Volume40
Issue number1
Pages (from-to)6-19
Number of pages14
ISSN0301-1526
DOIs
Publication statusPublished - 01.2011

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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