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Synthesis of heteroaryl substituted α-mercapto acids from thiomalic acid using hexafluoroacetone as protecting and activating reagent

Ksenia Pumpor, Elisabeth Windeisen, Klaus Burger*

*Corresponding author for this work

Abstract

The synthesis of heterocyclic α-mercapto acids starting from (RS)-thiomalic acid using hexafluoroacetone as protecting and activating agent is described. The new compounds are useful building blocks for peptide and depsipeptide modification as well as for drug design.

Original languageEnglish
JournalJournal of Heterocyclic Chemistry
Volume40
Issue number3
Pages (from-to)435-442
Number of pages8
ISSN0022-152X
DOIs
Publication statusPublished - 2003

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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