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Switching between Up and Down States in a conductance-based cortex model

Arne Weigenand, Hong-Viet V. Ngo, David Higgins, Thomas Martinetz, Jens Christian Claussen

Abstract

In a recent experiment [1] investigated the onand off switching of bursting activity in ferret brain slices. This experiment is seen as a paradigmatic system towards the understanding of the emergence of cortical slow waves. The basic dynamics can be modeled by a simplified discretized integrateand- fire model having intrinsic inhibitory currents but lacking inhibitory connections [2]. Here we use a conductance-based model to reproduce the spike-burst dynamics and the triggering of Up–states as obeserved in [1].
Original languageEnglish
Pages1-4
Number of pages4
Publication statusPublished - 07.2010
EventPROCEEDINGS OF BIOSIGNAL 2010 - Berlin, Germany
Duration: 14.07.201016.07.2010

Conference

ConferencePROCEEDINGS OF BIOSIGNAL 2010
Country/TerritoryGermany
CityBerlin
Period14.07.1016.07.10

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 9 - Industry, Innovation, and Infrastructure
    SDG 9 Industry, Innovation, and Infrastructure

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