Swept source optical coherence microscopy using a Fourier domain mode-locked laser

Shu-Wei Huang, Aaron D. Aguirre, Robert A. Huber, Desmond C. Adler, James G. Fujimoto

Abstract

Swept source optical coherence microscopy (OCM) enables cellular resolution en face imaging as well as integration with optical coherence tomography (OCT) cross sectional imaging. A buffered Fourier domain mode-locked (FDML) laser light source provides high speed, three dimensional imaging. Image resolutions of 1.6 μm × 8 μm (transverse × axial) with a 220 μm × 220 μm field of view and sensitivity higher than 98 dB are achieved. Three dimensional cellular imaging is demonstrated in vivo in the Xenopus laevis tadpole and ex vivo in the rat kidney and human colon.
Original languageEnglish
JournalOpt. Express
Volume15
Issue number10
Pages (from-to)6210-6217
Number of pages8
DOIs
Publication statusPublished - 01.05.2007

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