Abstract
Aim: The goal of this study was to identify prognostic factors of survival in patients receiving palliative external-beam radiotherapy (EBRT) for advanced liver cancer. Patients and Methods: Seventeen patients irradiated for advanced liver cancer were retrospectively evaluated. Fourteen patients had metastatic disease, three had locally advanced disease. Six variables were investigated for survival: age at EBRT, time from liver cancer diagnosis to EBRT, number of involved metastatic sites, gender, Eastern Cooperative Oncology Group (ECOG) performance score, radiation dose. Results: On univariate analyses, time from liver cancer diagnosis to EBRT >12 months (p=0.040), only 0-1 metastatic sites (p=0.003) and ECOG performance score 1-2 (p<0.001) were positively correlated with survival. On Cox regression analysis, the number of metastatic sites (risk ratio=4.68, p=0.053) and ECOG performance score (risk ratio=4.68, p=0.056) showed a strong trend for association with survival. Conclusion: Predictors of survival were found that can facilitate choosing the optimal treatment for individual patients with liver cancer assigned to palliative EBRT.
| Original language | English |
|---|---|
| Journal | Anticancer Research |
| Volume | 37 |
| Issue number | 1 |
| Pages (from-to) | 203-206 |
| Number of pages | 4 |
| ISSN | 0250-7005 |
| DOIs | |
| Publication status | Published - 01.2017 |
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
