TY - JOUR
T1 - Survival after out-of-hospital cardiac arrest in Europe - Results of the EuReCa TWO study
AU - Gräsner, Jan Thorsten
AU - Wnent, Jan
AU - Herlitz, Johan
AU - Perkins, Gavin D.
AU - Lefering, Rolf
AU - Tjelmeland, Ingvild
AU - Koster, Rudolph W.
AU - Masterson, Siobhán
AU - Rossell-Ortiz, Fernando
AU - Maurer, Holger
AU - Böttiger, Bernd W.
AU - Moertl, Maximilian
AU - Mols, Pierre
AU - Alihodžić, Hajriz
AU - Hadžibegović, Irzal
AU - Ioannides, Marios
AU - Truhlář, Anatolij
AU - Wissenberg, Mads
AU - Salo, Ari
AU - Escutnaire, Josephine
AU - Nikolaou, Nikolaos
AU - Nagy, Eniko
AU - Jonsson, Bergthor Steinn
AU - Wright, Peter
AU - Semeraro, Federico
AU - Clarens, Carlo
AU - Beesems, Steffie
AU - Cebula, Grzegorz
AU - Correia, Vitor H.
AU - Cimpoesu, Diana
AU - Raffay, Violetta
AU - Trenkler, Stefan
AU - Markota, Andrej
AU - Strömsöe, Anneli
AU - Burkart, Roman
AU - Booth, Scott
AU - Bossaert, Leo
N1 - Funding Information:
The EuReCa TWO study was supported by the ERC Research NET. The authors furthermore want to thank the EuReCa TWO Steering Committee and Study Management Team, namely Jan-Thorsten Gräsner, Leo Bossaert, Rudolph W. Koster, Johan Herlitz, Bernd W. Böttiger, Ingvild Tjelmeland, Siobhán Masterson, Jan Wnent, Fernando Rossel-Ortiz, Holger Maurer, and Gavin D. Perkins as well as the statistician Rolf Lefering for the huge effort made in running the study.
Publisher Copyright:
© 2020 Elsevier B.V.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/3/1
Y1 - 2020/3/1
N2 - Background: The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. Methods: This prospective, multicentre study involved the collection of registry-based data over a three-month period (1st October 2017 to 31st December 2017). The core study dataset complied with the Utstein-style. Primary outcomes were return of spontaneous circulation (ROSC) and survival to hospital admission. Secondary outcome was survival to hospital discharge. Results: All 28 countries provided data, covering a total population of 178,879,118. A total of 37,054 OHCA were confirmed, with CPR being started in 25,171 cases. The bystander cardiopulmonary resuscitation (CPR) rate ranged from 13% to 82% between countries (average: 58%). In one third of cases (33%) ROSC was achieved and 8% of patients were discharged from hospital alive. Survival to hospital discharge was higher in patients when a bystander performed CPR with ventilations, compared to compression-only CPR (14% vs. 8% respectively). Conclusion: In addition to increasing our understanding of the role of bystander CPR within Europe, EuReCa TWO has confirmed large variation in OHCA incidence, characteristics and outcome, and highlighted the extent to which OHCA is a public health burden across Europe. Unexplained variation remains and the EuReCa network has a continuing role to play in improving the quality management of resuscitation.
AB - Background: The epidemiology and outcome after out-of-hospital cardiac arrest (OHCA) varies across Europe. Following on from EuReCa ONE, the aim of this study was to further explore the incidence of and outcomes from OHCA in Europe and to improve understanding of the role of the bystander. Methods: This prospective, multicentre study involved the collection of registry-based data over a three-month period (1st October 2017 to 31st December 2017). The core study dataset complied with the Utstein-style. Primary outcomes were return of spontaneous circulation (ROSC) and survival to hospital admission. Secondary outcome was survival to hospital discharge. Results: All 28 countries provided data, covering a total population of 178,879,118. A total of 37,054 OHCA were confirmed, with CPR being started in 25,171 cases. The bystander cardiopulmonary resuscitation (CPR) rate ranged from 13% to 82% between countries (average: 58%). In one third of cases (33%) ROSC was achieved and 8% of patients were discharged from hospital alive. Survival to hospital discharge was higher in patients when a bystander performed CPR with ventilations, compared to compression-only CPR (14% vs. 8% respectively). Conclusion: In addition to increasing our understanding of the role of bystander CPR within Europe, EuReCa TWO has confirmed large variation in OHCA incidence, characteristics and outcome, and highlighted the extent to which OHCA is a public health burden across Europe. Unexplained variation remains and the EuReCa network has a continuing role to play in improving the quality management of resuscitation.
UR - http://www.scopus.com/inward/record.url?scp=85079158573&partnerID=8YFLogxK
U2 - 10.1016/j.resuscitation.2019.12.042
DO - 10.1016/j.resuscitation.2019.12.042
M3 - Journal articles
C2 - 32027980
AN - SCOPUS:85079158573
SN - 0300-9572
VL - 148
SP - 218
EP - 226
JO - Resuscitation
JF - Resuscitation
ER -
