Superparamagnetic Iron Oxide Nanoparticles: Evaluation of Stability of SPIONs in Different Milieu for Magnetic Particle Imaging

Kerstin Lüdtke-Buzug, Céline Borchers

Abstract

Today, a variety of different nanoparticles are used in various applications. In particular, super-paramagnetic iron oxide nanoparticles (or SPIONs) are used in vitro for cell separation and in vivo for hyperthermia or as contrast agent for magnetic resonance imaging (MRI). However, in Magnetic Particle Imaging (MPI), SPIONs play a fundamental role as tracer material. In addition to the overall size of the particles and the particle coating, which are important for medical applications, it is the magnetic core diameter that is relevant for the performance in MPI applications. In general, for in vivo applications, the stability of the particles is of key importance. Therefore, in this paper, the stability of the SPIONs have been analyzed in different particle suspension media.
Original languageEnglish
Title of host publicationMagnetic Particle Imaging
EditorsThorsten M. Buzug, Jörn Borgert
Number of pages5
Volume140
PublisherSpringer Berlin Heidelberg
Publication date01.2012
Pages105-109
ISBN (Print)978-3-642-24132-1
ISBN (Electronic)978-3-642-24133-8
DOIs
Publication statusPublished - 01.2012
Event2th International Workshop on Magnetic Particle Imaging (IWMPI 2012) - Lübeck, Germany
Duration: 15.03.201216.03.2012
https://www.iwmpi.org/home/previous-conferences/2012/

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