1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

Dieter Ebert; Oliver Speck; Almuth König; Mathias Berger; Jürgen Hennig; Fritz Hohagen

doi:10.1016/S0925-4927(97)00016-4

¹H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

Dieter Ebert^*, Oliver Speck, Almuth König, Mathias Berger, Jürgen Hennig, Fritz Hohagen

^*Corresponding author for this work

Department of Psychiatry, Psychosomatics and Psychotherapie

University of Freiburg

145 Citations (Scopus)

Abstract

We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by ¹H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

Original language	English
Journal	Psychiatry Research - Neuroimaging
Volume	74
Issue number	3
Pages (from-to)	173-176
Number of pages	4
ISSN	0925-4927
DOIs	https://doi.org/10.1016/S0925-4927(97)00016-4
Publication status	Published - 04.07.1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 10 Reduced Inequalities

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

Access to Document

10.1016/S0925-4927(97)00016-4

Cite this

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abstract = "We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.",

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AU - Hennig, Jürgen

AU - Hohagen, Fritz

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