1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

Dieter Ebert*, Oliver Speck, Almuth König, Mathias Berger, Jürgen Hennig, Fritz Hohagen

*Corresponding author for this work
129 Citations (Scopus)

Abstract

We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

Original languageEnglish
JournalPsychiatry Research - Neuroimaging
Volume74
Issue number3
Pages (from-to)173-176
Number of pages4
ISSN0925-4927
DOIs
Publication statusPublished - 04.07.1997

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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