1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

Dieter Ebert; Oliver Speck; Almuth König; Mathias Berger; Jürgen Hennig; Fritz Hohagen

doi:10.1016/S0925-4927(97)00016-4

¹H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

Dieter Ebert^*, Oliver Speck, Almuth König, Mathias Berger, Jürgen Hennig, Fritz Hohagen

^*Corresponding author for this work

Clinic of Psychiatry and Psychotherapy

University of Freiburg

129 Citations (Scopus)

Abstract

We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by ¹H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

Original language	English
Journal	Psychiatry Research - Neuroimaging
Volume	74
Issue number	3
Pages (from-to)	173-176
Number of pages	4
ISSN	0925-4927
DOIs	https://doi.org/10.1016/S0925-4927(97)00016-4
Publication status	Published - 04.07.1997

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S0925-4927(97)00016-4

Cite this

@article{73fd0becd1d4453f89c73cb4b992dd91,

title = "1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum",

abstract = "We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.",

author = "Dieter Ebert and Oliver Speck and Almuth K{\"o}nig and Mathias Berger and J{\"u}rgen Hennig and Fritz Hohagen",

year = "1997",

month = jul,

day = "4",

doi = "10.1016/S0925-4927(97)00016-4",

language = "English",

volume = "74",

pages = "173--176",

journal = "Psychiatry Research - Neuroimaging",

issn = "0925-4927",

number = "3",

}

TY - JOUR

T1 - 1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: Evidence for neural loss in the cingulate gyrus and the right striatum

AU - Ebert, Dieter

AU - Speck, Oliver

AU - König, Almuth

AU - Berger, Mathias

AU - Hennig, Jürgen

AU - Hohagen, Fritz

PY - 1997/7/4

Y1 - 1997/7/4

N2 - We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

AB - We compared 12 patients with obsessive-compulsive disorder (OCD) and six control subjects by 1H-magnetic resonance spectroscopy. Significantly lower relative N-acetyl-aspartate (NAA) levels were found in the right striatum of OCD patients, as well as a decrease of anterior cingulate NAA that correlated with severity of illness. Age and sex were correlated to striatal NAA levels.

UR - http://www.scopus.com/inward/record.url?scp=0031552516&partnerID=8YFLogxK

U2 - 10.1016/S0925-4927(97)00016-4

DO - 10.1016/S0925-4927(97)00016-4

M3 - Journal articles

C2 - 9255862

AN - SCOPUS:0031552516

SN - 0925-4927

VL - 74

SP - 173

EP - 176

JO - Psychiatry Research - Neuroimaging

JF - Psychiatry Research - Neuroimaging

IS - 3

ER -