Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study

Erik Lauterbach; Bernd Ahrens; Werner Felber; Bruno Muller-Oerlinghausen; Birgit Kilb; Gerd Bischof; Isabella Heuser; Petra Werner; Barbara Hawellek; Wolfgang Maier; Ute Lewitzka; Oliver Pogarell; Ulrich Hegerl; Thomas Bronisch; Kneginja Richter; Günther Niklewski; Andreas Broocks; Fritz Hohagen

doi:10.1080/13811110590512886

Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study

Erik Lauterbach^*, Bernd Ahrens, Werner Felber, Bruno Muller-Oerlinghausen, Birgit Kilb, Gerd Bischof, Isabella Heuser, Petra Werner, Barbara Hawellek, Wolfgang Maier, Ute Lewitzka, Oliver Pogarell, Ulrich Hegerl, Thomas Bronisch, Kneginja Richter, Günther Niklewski, Andreas Broocks, Fritz Hohagen

^*Corresponding author for this work

15 Citations (Scopus)

Abstract

Several studies have shown that there is a significantly increased risk of suicide related mortality in patients with a positive history of suicide attempts. The SUPLI-Study is the first prospective, randomized, double blind, placebo controlled multi-center trial focusing on the proposed suicide preventive effects of lithium in patients with suicidal behavior but not suffering from bipolar disorder or recurrent major depressive disorder. Patients with a recent history of a suicide attempt are treated with lithium versus placebo during a 12 month period. The hypothesis is that lithium treatment will lead to a 50% reduction of suicidal behavior. The protocol of the study and preliminary results an presented.

Original language	English
Journal	Archives of Suicide Research
Volume	9
Issue number	1
Pages (from-to)	27-34
Number of pages	8
ISSN	1381-1118
DOIs	https://doi.org/10.1080/13811110590512886
Publication status	Published - 2005

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/13811110590512886

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Lauterbach, E., Ahrens, B., Felber, W., Muller-Oerlinghausen, B., Kilb, B., Bischof, G., Heuser, I., Werner, P., Hawellek, B., Maier, W., Lewitzka, U., Pogarell, O., Hegerl, U., Bronisch, T., Richter, K., Niklewski, G., Broocks, A., & Hohagen, F. (2005). Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study. Archives of Suicide Research, 9(1), 27-34. https://doi.org/10.1080/13811110590512886

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abstract = "Several studies have shown that there is a significantly increased risk of suicide related mortality in patients with a positive history of suicide attempts. The SUPLI-Study is the first prospective, randomized, double blind, placebo controlled multi-center trial focusing on the proposed suicide preventive effects of lithium in patients with suicidal behavior but not suffering from bipolar disorder or recurrent major depressive disorder. Patients with a recent history of a suicide attempt are treated with lithium versus placebo during a 12 month period. The hypothesis is that lithium treatment will lead to a 50% reduction of suicidal behavior. The protocol of the study and preliminary results an presented.",

author = "Erik Lauterbach and Bernd Ahrens and Werner Felber and Bruno Muller-Oerlinghausen and Birgit Kilb and Gerd Bischof and Isabella Heuser and Petra Werner and Barbara Hawellek and Wolfgang Maier and Ute Lewitzka and Oliver Pogarell and Ulrich Hegerl and Thomas Bronisch and Kneginja Richter and G{\"u}nther Niklewski and Andreas Broocks and Fritz Hohagen",

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Lauterbach, E, Ahrens, B, Felber, W, Muller-Oerlinghausen, B, Kilb, B, Bischof, G, Heuser, I, Werner, P, Hawellek, B, Maier, W, Lewitzka, U, Pogarell, O, Hegerl, U, Bronisch, T, Richter, K, Niklewski, G, Broocks, A & Hohagen, F 2005, 'Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study', Archives of Suicide Research, vol. 9, no. 1, pp. 27-34. https://doi.org/10.1080/13811110590512886

TY - JOUR

T1 - Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study

AU - Lauterbach, Erik

AU - Ahrens, Bernd

AU - Felber, Werner

AU - Muller-Oerlinghausen, Bruno

AU - Kilb, Birgit

AU - Bischof, Gerd

AU - Heuser, Isabella

AU - Werner, Petra

AU - Hawellek, Barbara

AU - Maier, Wolfgang

AU - Lewitzka, Ute

AU - Pogarell, Oliver

AU - Hegerl, Ulrich

AU - Bronisch, Thomas

AU - Richter, Kneginja

AU - Niklewski, Günther

AU - Broocks, Andreas

AU - Hohagen, Fritz

PY - 2005

Y1 - 2005

N2 - Several studies have shown that there is a significantly increased risk of suicide related mortality in patients with a positive history of suicide attempts. The SUPLI-Study is the first prospective, randomized, double blind, placebo controlled multi-center trial focusing on the proposed suicide preventive effects of lithium in patients with suicidal behavior but not suffering from bipolar disorder or recurrent major depressive disorder. Patients with a recent history of a suicide attempt are treated with lithium versus placebo during a 12 month period. The hypothesis is that lithium treatment will lead to a 50% reduction of suicidal behavior. The protocol of the study and preliminary results an presented.

AB - Several studies have shown that there is a significantly increased risk of suicide related mortality in patients with a positive history of suicide attempts. The SUPLI-Study is the first prospective, randomized, double blind, placebo controlled multi-center trial focusing on the proposed suicide preventive effects of lithium in patients with suicidal behavior but not suffering from bipolar disorder or recurrent major depressive disorder. Patients with a recent history of a suicide attempt are treated with lithium versus placebo during a 12 month period. The hypothesis is that lithium treatment will lead to a 50% reduction of suicidal behavior. The protocol of the study and preliminary results an presented.

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U2 - 10.1080/13811110590512886

DO - 10.1080/13811110590512886

M3 - Journal articles

C2 - 16040577

AN - SCOPUS:17044365778

SN - 1381-1118

VL - 9

SP - 27

EP - 34

JO - Archives of Suicide Research

JF - Archives of Suicide Research

IS - 1

ER -

Suicide Prevention by Lithium (SUPLI) - Challenges of a multi-center prospective study

Abstract

Research Areas and Centers

UN SDGs

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