Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations

Suzuyo Komeda; Nobuhisa Tateno; Ann Marina Detje; Xibo Wang; Yue Zhu; Atsuko Furukawa; Rion Morishita; Ibrahim Abd El-Sadek; Shuichi Makita; Yoko Miura; Satoshi Matsusaka; Yoshiaki Yasuno

doi:10.1364/ECBO.2025.S4B.4

Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations

Suzuyo Komeda, Nobuhisa Tateno, Ann Marina Detje, Xibo Wang, Yue Zhu, Atsuko Furukawa, Rion Morishita, Ibrahim Abd El-Sadek, Shuichi Makita, Yoko Miura, Satoshi Matsusaka, Yoshiaki Yasuno

Abstract

High-resolution and functional imaging of in vitro samples including cancer spheroids is demonstrated with a full-field swept-source optical coherence tomography device, where computational augmentations enable long imaging depth, speckle-free imaging, and label-free cellular activity imaging.

Original language	English
Title of host publication	European Conferences on Biomedical Optics 2025
Publisher	Optica Publishing Group
Publication date	2025
Pages	S4B.4
DOIs	https://doi.org/10.1364/ECBO.2025.S4B.4
Publication status	Published - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 9 Industry, Innovation, and Infrastructure

Access to Document

10.1364/ECBO.2025.S4B.4

https://opg.optica.org/abstract.cfm?URI=ECBO-2025-S4B.4

Cite this

Komeda, S., Tateno, N., Detje, A. M., Wang, X., Zhu, Y., Furukawa, A., Morishita, R., El-Sadek, I. A., Makita, S., Miura, Y., Matsusaka, S., & Yasuno, Y. (2025). Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations. In European Conferences on Biomedical Optics 2025 (pp. S4B.4). Optica Publishing Group. https://doi.org/10.1364/ECBO.2025.S4B.4

@inproceedings{c034f84ff2434e64996bd58d7b94c478,

title = "Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations",

abstract = "High-resolution and functional imaging of in vitro samples including cancer spheroids is demonstrated with a full-field swept-source optical coherence tomography device, where computational augmentations enable long imaging depth, speckle-free imaging, and label-free cellular activity imaging.",

author = "Suzuyo Komeda and Nobuhisa Tateno and Detje, \{Ann Marina\} and Xibo Wang and Yue Zhu and Atsuko Furukawa and Rion Morishita and El-Sadek, \{Ibrahim Abd\} and Shuichi Makita and Yoko Miura and Satoshi Matsusaka and Yoshiaki Yasuno",

year = "2025",

doi = "10.1364/ECBO.2025.S4B.4",

language = "English",

pages = "S4B.4",

booktitle = "European Conferences on Biomedical Optics 2025",

publisher = "Optica Publishing Group",

}

Komeda, S, Tateno, N, Detje, AM, Wang, X, Zhu, Y, Furukawa, A, Morishita, R, El-Sadek, IA, Makita, S, Miura, Y, Matsusaka, S & Yasuno, Y 2025, Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations. in European Conferences on Biomedical Optics 2025. Optica Publishing Group, pp. S4B.4. https://doi.org/10.1364/ECBO.2025.S4B.4

Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations. / Komeda, Suzuyo; Tateno, Nobuhisa; Detje, Ann Marina et al.
European Conferences on Biomedical Optics 2025. Optica Publishing Group, 2025. p. S4B.4.

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Structural and metabolic imaging of cancer spheroids by Zero-NA full-field optical coherence microscope with computational augmentations

AU - Komeda, Suzuyo

AU - Tateno, Nobuhisa

AU - Detje, Ann Marina

AU - Wang, Xibo

AU - Zhu, Yue

AU - Furukawa, Atsuko

AU - Morishita, Rion

AU - El-Sadek, Ibrahim Abd

AU - Makita, Shuichi

AU - Miura, Yoko

AU - Matsusaka, Satoshi

AU - Yasuno, Yoshiaki

PY - 2025

Y1 - 2025

N2 - High-resolution and functional imaging of in vitro samples including cancer spheroids is demonstrated with a full-field swept-source optical coherence tomography device, where computational augmentations enable long imaging depth, speckle-free imaging, and label-free cellular activity imaging.

AB - High-resolution and functional imaging of in vitro samples including cancer spheroids is demonstrated with a full-field swept-source optical coherence tomography device, where computational augmentations enable long imaging depth, speckle-free imaging, and label-free cellular activity imaging.

U2 - 10.1364/ECBO.2025.S4B.4

DO - 10.1364/ECBO.2025.S4B.4

M3 - Conference contribution

SP - S4B.4

BT - European Conferences on Biomedical Optics 2025

PB - Optica Publishing Group

ER -