Structural and functional imaging with extended focus dark-field OCT at 1300nm

Cedric Blatter; Branislav Grajciar; Robert Huber; Rainer A Leitgeb

doi:10.1117/12.875594

Structural and functional imaging with extended focus dark-field OCT at 1300nm

Cedric Blatter, Branislav Grajciar, Robert Huber, Rainer A Leitgeb

Institute of Biomedical Optics

Abstract

We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.

Original language	English
Title of host publication	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
Editors	James G Fujimoto, Joseph A Izatt, Valery V Tuchin
Number of pages	6
Volume	78891D
Publisher	SPIE
Publication date	11.02.2011
Pages	78891D-78891D-6
ISBN (Print)	9780819484260
DOIs	https://doi.org/10.1117/12.875594
Publication status	Published - 11.02.2011
Event	SPIE BIOS - San Francisco, United States Duration: 22.01.2011 → 27.01.2011

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Blatter, C., Grajciar, B., Huber, R., & Leitgeb, R. A. (2011). Structural and functional imaging with extended focus dark-field OCT at 1300nm. In J. G. Fujimoto, J. A. Izatt, & V. V. Tuchin (Eds.), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV (Vol. 78891D , pp. 78891D-78891D-6). (Proceedings of SPIE; Vol. 7889). SPIE. https://doi.org/10.1117/12.875594

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title = "Structural and functional imaging with extended focus dark-field OCT at 1300nm",

abstract = "We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.",

author = "Cedric Blatter and Branislav Grajciar and Robert Huber and Leitgeb, {Rainer A}",

year = "2011",

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doi = "10.1117/12.875594",

language = "English",

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series = "Proceedings of SPIE",

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editor = "Fujimoto, {James G} and Izatt, {Joseph A} and Tuchin, {Valery V}",

booktitle = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV",

note = "SPIE BIOS ; Conference date: 22-01-2011 Through 27-01-2011",

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Blatter, C, Grajciar, B, Huber, R & Leitgeb, RA 2011, Structural and functional imaging with extended focus dark-field OCT at 1300nm. in JG Fujimoto, JA Izatt & VV Tuchin (eds), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV. vol. 78891D , Proceedings of SPIE, vol. 7889, SPIE, pp. 78891D-78891D-6, SPIE BIOS, San Francisco, California, United States, 22.01.11. https://doi.org/10.1117/12.875594

Structural and functional imaging with extended focus dark-field OCT at 1300nm. / Blatter, Cedric; Grajciar, Branislav; Huber, Robert et al.
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV. ed. / James G Fujimoto; Joseph A Izatt; Valery V Tuchin. Vol. 78891D SPIE, 2011. p. 78891D-78891D-6 (Proceedings of SPIE; Vol. 7889).

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Structural and functional imaging with extended focus dark-field OCT at 1300nm

AU - Blatter, Cedric

AU - Grajciar, Branislav

AU - Huber, Robert

AU - Leitgeb, Rainer A

PY - 2011/2/11

Y1 - 2011/2/11

N2 - We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.

AB - We present an extended focus FDOCT setup with FDML swept source centered at 1310nm. The illumination, preserving its lateral extend over a large depth range thanks to the use of a Bessel beam, is decoupled from the Gaussian detection in order to increase the global sensitivity. The efficient spatial separation enables dark-field imaging. In-vivo measurements in the skin were performed to demonstrate the gain in lateral resolution while preserving the imaging depth. More, the calculation of the speckle variance between B-Scans allows a clear visualization of the microvasculature.

U2 - 10.1117/12.875594

DO - 10.1117/12.875594

M3 - Conference contribution

SN - 9780819484260

VL - 78891D

T3 - Proceedings of SPIE

SP - 78891D-78891D-6

BT - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV

A2 - Fujimoto, James G

A2 - Izatt, Joseph A

A2 - Tuchin, Valery V

PB - SPIE

T2 - SPIE BIOS

Y2 - 22 January 2011 through 27 January 2011

ER -

Structural and functional imaging with extended focus dark-field OCT at 1300nm

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