Strahlentherapie nach brusterhaltender Operation beim Mammakarzinom: Aktuelle Entwicklungen und Studienkonzepte

Translated title of the contribution: Radiation therapy after breast-conserving surgery for breast cancer: Current developments and study concepts

Jürgen Dunst*, René Baumann, Ping Jiang, Constanze Walldorf, Dirk Bauerschlag

*Corresponding author for this work

Abstract

The radiation therapy for breast cancer established in the 1980s has experienced many relevant modifications. Research has improved the understanding of the mode of action but at the same time has thrown up questions. The focus is on radiation treatment after breast-conserving surgery. Current results and running studies, e.g. the Working Group of Radiation Oncology (ARO) study are presented. Also addressed is the desideratum for the necessary scepsis (e.g. limitations due to a too short total irradiation time for large volumes and excessive demands on the repair capacity of healthy tissue) in view of the attempts to minimize the treatment times even further. With the introduction of hypofractionization, the advantage of partial breast irradiation has been reduced with respect to the treatment time; therefore, a trend away from partial breast irradiation would be plausible and can already be observed in the USA; nevertheless, this remains the only meaningful radiotherapeutic option for breast-conserving operations for recurrences following irradiation.

Translated title of the contributionRadiation therapy after breast-conserving surgery for breast cancer: Current developments and study concepts
Original languageGerman
JournalGynakologe
Volume50
Issue number11
Pages (from-to)879-884
Number of pages6
ISSN0017-5994
DOIs
Publication statusPublished - 01.11.2017

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