TY - JOUR
T1 - Stereotactic Body Radiotherapy Provides Excellent Long-Term Local Control of Very Few Lung Metastases
AU - Janssen, Stefan
AU - Käsmann, Lukas
AU - Rudat, Volker
AU - Rades, Dirk
N1 - Publisher Copyright:
Copyright © 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.
Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 2016/3/1
Y1 - 2016/3/1
N2 - AIM: To evaluate treatment outcomes after stereotactic body radiotherapy (SBRT) for a limited number of lung metastases mainly focusing on local control.PATIENTS AND METHODS: Forty-six patients receiving SBRT for 1-3 lung metastases were retrospectively evaluated. Local control, freedom from distant progression and overall survival were evaluated in the entire series. In addition, nine factors (gender, age, performance status, interval between cancer diagnosis and SBRT, primary tumor type, other metastases, main site and number of lesions, irradiated volume, SBRT dose) were evaluated for local control.RESULTS: Local control rates at 1, 2 and 3 years were 93%, 93% and 78%, respectively. Rates of freedom from distant progression were 57%, 38% and 29%, respectively, and overall survival rates were 66%, 56% and 36%, respectively. Only one patient (2%) experienced radiation-induced pneumonitis.CONCLUSION: SBRT administered for very few lung metastases resulted in excellent long-term local control rates and was associated with very little toxicity.
AB - AIM: To evaluate treatment outcomes after stereotactic body radiotherapy (SBRT) for a limited number of lung metastases mainly focusing on local control.PATIENTS AND METHODS: Forty-six patients receiving SBRT for 1-3 lung metastases were retrospectively evaluated. Local control, freedom from distant progression and overall survival were evaluated in the entire series. In addition, nine factors (gender, age, performance status, interval between cancer diagnosis and SBRT, primary tumor type, other metastases, main site and number of lesions, irradiated volume, SBRT dose) were evaluated for local control.RESULTS: Local control rates at 1, 2 and 3 years were 93%, 93% and 78%, respectively. Rates of freedom from distant progression were 57%, 38% and 29%, respectively, and overall survival rates were 66%, 56% and 36%, respectively. Only one patient (2%) experienced radiation-induced pneumonitis.CONCLUSION: SBRT administered for very few lung metastases resulted in excellent long-term local control rates and was associated with very little toxicity.
UR - http://www.scopus.com/inward/record.url?scp=85021855227&partnerID=8YFLogxK
M3 - Journal articles
C2 - 26912828
AN - SCOPUS:85021855227
SN - 0258-851X
VL - 30
SP - 155
EP - 157
JO - In vivo (Athens, Greece)
JF - In vivo (Athens, Greece)
IS - 2
ER -
