Spontaneous liver rupture after treatment with drug-eluting beads

C. O. Ritter; M. Wartenberg; A. Mottok; U. Steger; J. P. Goltz; D. Hahn; R. Kickuth

doi:10.1007/s00270-011-0145-7

Spontaneous liver rupture after treatment with drug-eluting beads

C. O. Ritter^*, M. Wartenberg, A. Mottok, U. Steger, J. P. Goltz, D. Hahn, R. Kickuth

^*Corresponding author for this work

Clinic of Radiology and Nuclear Medicine

University of Würzburg

12 Citations (Scopus)

Abstract

Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

Original language	English
Journal	CardioVascular and Interventional Radiology
Volume	35
Issue number	1
Pages (from-to)	198-202
Number of pages	5
ISSN	0174-1551
DOIs	https://doi.org/10.1007/s00270-011-0145-7
Publication status	Published - 01.02.2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s00270-011-0145-7

Cite this

@article{822cadfc237a4af781f3069c1872e14e,

title = "Spontaneous liver rupture after treatment with drug-eluting beads",

abstract = "Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.",

author = "Ritter, \{C. O.\} and M. Wartenberg and A. Mottok and U. Steger and Goltz, \{J. P.\} and D. Hahn and R. Kickuth",

year = "2012",

month = feb,

day = "1",

doi = "10.1007/s00270-011-0145-7",

language = "English",

volume = "35",

pages = "198--202",

journal = "CardioVascular and Interventional Radiology",

issn = "0174-1551",

publisher = "Springer",

number = "1",

}

TY - JOUR

T1 - Spontaneous liver rupture after treatment with drug-eluting beads

AU - Ritter, C. O.

AU - Wartenberg, M.

AU - Mottok, A.

AU - Steger, U.

AU - Goltz, J. P.

AU - Hahn, D.

AU - Kickuth, R.

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

AB - Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is preceded by reactive tissue edema and intratumerous bleeding, leading to a rapid expansion of tumour mass with risk of extrahepatic bleeding in the case of subcapsular localisation. This case report discusses a sudden, unexpected lethal complication in a 74 year-old male patient treated with TACE using DC Bead loaded with doxorubicin (DEBDOX) in a progressive multifocal HCC.

UR - https://www.scopus.com/pages/publications/84857036994

U2 - 10.1007/s00270-011-0145-7

DO - 10.1007/s00270-011-0145-7

M3 - Journal articles

C2 - 21431968

AN - SCOPUS:84857036994

SN - 0174-1551

VL - 35

SP - 198

EP - 202

JO - CardioVascular and Interventional Radiology

JF - CardioVascular and Interventional Radiology

IS - 1

ER -

Spontaneous liver rupture after treatment with drug-eluting beads

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this